Evidence map›Paper›PMID 40956501›Full record

ArticleOdontology2026

Effect of incorporating calcium polyphosphate submicroparticles into bleaching gels on enamel surface loss after erosive challenge.

Carolina Meneghin Barbosa, Mariangela Ivette Guanipa Ortiz, Julliana Andrade Da Silva, Waldemir Francisco Vieira-Junior, Flávio Henrique Baggio Aguiar, Klaus Rischka, Débora Alves Nunes Leite Lima

Abstract read
PubMed Publisher
In one paragraph

Article in Odontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Carolina Meneghin BarbosaDepartamento de Odontologia Restauradora, Faculdade de Odontologia de Piracicaba (FOP), Universidade Estadual de Campinas (UNICAMP), P.O. BOX 52, Piracicaba, SP, 13414-903, Brazil.ORCID http://orcid.org/0000-0003-3223-3952
Mariangela Ivette Guanipa OrtizDepartamento de Odontologia Restauradora, Faculdade de Odontologia de Piracicaba (FOP), Universidade Estadual de Campinas (UNICAMP), P.O. BOX 52, Piracicaba, SP, 13414-903, Brazil.ORCID http://orcid.org/0000-0003-1191-1339
Julliana Andrade Da SilvaDepartamento de Odontologia Restauradora, Faculdade de Odontologia de Piracicaba (FOP), Universidade Estadual de Campinas (UNICAMP), P.O. BOX 52, Piracicaba, SP, 13414-903, Brazil.ORCID http://orcid.org/0000-0003-0700-519X
Waldemir Francisco Vieira-JuniorDepartamento de Odontologia Restauradora, Faculdade de Odontologia de Piracicaba (FOP), Universidade Estadual de Campinas (UNICAMP), P.O. BOX 52, Piracicaba, SP, 13414-903, Brazil.ORCID http://orcid.org/0000-0001-8226-3100
Flávio Henrique Baggio AguiarDepartamento de Odontologia Restauradora, Faculdade de Odontologia de Piracicaba (FOP), Universidade Estadual de Campinas (UNICAMP), P.O. BOX 52, Piracicaba, SP, 13414-903, Brazil.ORCID http://orcid.org/0000-0003-3389-5536
Klaus RischkaFraunhofer Institute for Manufacturing Technology and Advanced Materials IFAM, Bremen, Germany.ORCID http://orcid.org/0000-0003-3427-4037
Débora Alves Nunes Leite LimaDepartamento de Odontologia Restauradora, Faculdade de Odontologia de Piracicaba (FOP), Universidade Estadual de Campinas (UNICAMP), P.O. BOX 52, Piracicaba, SP, 13414-903, Brazil. dalima@unicamp.br.ORCID http://orcid.org/0000-0001-5457-3347

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 0001
6 · The paper itself

Abstract

This in vitro study aimed to evaluate the changes in surface integrity of dental enamel after bleaching using gels with different compositions followed by an erosive challenge. Bovine enamel specimens (4 × 4 × 2 mm; n = 12/group) stored in artificial saliva were treated with bleaching gels containing carbamide peroxide (CP) or hydrogen peroxide (HP) with or without calcium polyphosphate (CaPP) followed by an erosive challenge. In Experiment 1, 10% commercial CP (CPC), CPC + 2% NaF, 10% manipulated CP (CPM), CPM + 2% NaF, 10% CP + 0.5 wt% CaPP, 10% CP + 1.5 wt% CaPP, manipulated gel without CP, or no bleaching were applied for 14 days. In Experiment 2, CP was switched with 35% HP, and all gels were applied for two sessions. Thereafter, all samples were subjected to a 5-day erosive challenge using 1% citric acid (pH 3.5) for 120 s. Enamel surface loss was assessed using contact profilometry and scanning electron microscopy (SEM). Statistical analysis was performed using a generalized linear model (α = 0.05). Compared with that in the CP + 0.5% CaPP and HP + 0.5% CaPP groups, enamel loss was significantly greater in the CPM and CPC groups and HPM and HPC groups in Experiments 1 and 2, respectively. SEM analysis revealed less surface degradation in the groups containing 0.5% CaPP, with greater preservation of the prismatic and interprismatic enamel structure. Both low- and high-concentration bleaching gels containing 0.5% CaPP improved enamel preservation after an erosive challenge compared to that with gels without CaPP. Thus, the addition of CaPP may help minimize enamel damage during bleaching by reducing mineral loss.

Indexed as

Calcium PhosphatesDental EnamelPolyphosphatesTooth BleachingTooth Bleaching AgentsTooth ErosionAnimalsCarbamide PeroxideCattleGelsHydrogen PeroxideIn Vitro TechniquesMicroscopy, Electron, ScanningPeroxidesSurface PropertiesUreaCalcium PhosphatesCarbamide PeroxideGelsHydrogen PeroxidePeroxidesPolyphosphatesTooth Bleaching AgentsUreaBleachingCarbamide peroxideErosive challengeHydrogen peroxidePolyphosphates

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.