Evidence map›Paper›PMID 40956398›Full record

ArticleJournal of robotic surgery2025

Does age affect functional and perioperative outcomes after robotic-assisted prostatectomy in localized prostate cancer?

Deerush Kannan Sakthivel, Pushan Prabhakar, Mohamed Javid Raja Iyub, Manuel Ozambela, Murugesan Manoharan

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Article in Journal of robotic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Deerush Kannan SakthivelDepartment of Urology, Baptist Health South Florida, Miami, USA. deerush92@gmail.com.
Pushan PrabhakarDepartment of Urology, Baptist Health South Florida, Miami, USA.
Mohamed Javid Raja IyubDepartment of Urology, Baptist Health South Florida, Miami, USA.
Manuel OzambelaDepartment of Urology, Baptist Health South Florida, Miami, USA.
Murugesan ManoharanDepartment of Urology, Baptist Health South Florida, Miami, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Robotic-assisted laparoscopic prostatectomy (RALP) is widely accepted for treating localized prostate cancer, particularly in low- and intermediate-risk groups. However, the impact of advancing age on postoperative continence recovery and complication rates remains uncertain, often influencing treatment decisions in elderly patients. To evaluate the influence of age on continence outcomes and perioperative complications following RALP in patients with low- and intermediate-risk prostate cancer. This retrospective study included 439 patients undergoing RALP, stratified into three age groups: ≤ 60 years (n = 133), 61-70 years (n = 221), and > 70 years (n = 85). Baseline demographic, perioperative, pathological, continence recovery, and biochemical recurrence outcomes were compared across groups. Continence was assessed at 3, 6, 12, and 24 months postoperatively. Complication rates were classified using the Clavien-Dindo system. Higher comorbidity scores (≥ 3) were more frequent in patients over 70 years (25.9% vs. 9% in ≤ 60 years, p = 0.022). Mean preoperative PSA was significantly higher in the oldest group (7.67 vs. 6.54 ng/mL, p = 0.039). Operative time and estimated blood loss were similar across groups (p = 0.138 and p = 0.677). Length of stay showed a trend toward longer hospitalization in older patients (≥ 3 days: 21.2% in > 70 vs. 7.5% in ≤ 60 years, p = 0.058). Pathological staging and Gleason grades were comparable (p > 0.3). Continence recovery at 3 months was similar (70.6-72.2%, p = 0.27), with slightly lower rates at 1 year in patients > 70 years (77.6% vs. 88.0% in ≤ 60). Biochemical recurrence rates and adjuvant therapy usage did not differ significantly (p > 0.6). Only 3 major complications exceeding Clavien-Dindo grade 2 were reported (p > 0.8). RALP is safe and effective across age groups, including elderly patients, with comparable oncologic and functional outcomes. Age alone should not preclude consideration of RALP in appropriately selected patients. These findings support individualized counseling and treatment planning to optimize outcomes in older adults.

Indexed as

ProstatectomyProstatic NeoplasmsRobotic Surgical ProceduresAgedAge FactorsHumansLaparoscopyLength of StayMaleMiddle AgedOperative TimePostoperative ComplicationsRetrospective StudiesTreatment OutcomeUrinary Incontinenceprostate cancerradical prostatectomyRobotic prostatectomyrobotic urology

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.