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ArticleClinical oral investigations2025

Clinical validation of a deep learning based application for quantitative assessment of dental plaque in fluorescence imaging.

Hang-Nga Mai, Sohee Kang, Hyeonjeong Go, Youn-Hee Choi, Eun Young Park, Eun-Kyong Kim

Abstract readValidation Study
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In one paragraph

Article in Clinical oral investigations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Hang-Nga MaiInstitute for Translational Research in Dentistry, Kyungpook National University, Daegu, Republic of Korea.
Sohee KangDepartment of Dentistry, College of Medicine, Yeungnam University, Daegu, Republic of Korea.
Hyeonjeong GoDepartment of Preventive Dentistry, School of Dentistry, Kyungpook National University, 2177 Dalgubeol-daero, Jung-gu, Daegu, 41944, Republic of Korea.
Youn-Hee ChoiInstitute for Translational Research in Dentistry, Kyungpook National University, Daegu, Republic of Korea.
Eun Young Park *Department of Dentistry, College of Medicine, Yeungnam University, Daegu, Republic of Korea.
Eun-Kyong Kim *Department of Preventive Dentistry, School of Dentistry, Kyungpook National University, 2177 Dalgubeol-daero, Jung-gu, Daegu, 41944, Republic of Korea. ekkim99@knu.ac.kr.

Funding

This work was supported by the National Research Foundation of Korea(NRF) grant funded by the Korea government(MSIT) RS-2024-00333398
6 · The paper itself

Abstract

aimEvaluating dental plaque is a fundamental task for periodontal health care, but it is subjective, time-consuming, and cumbersome. Therefore, this study aimed to develop and validate a web-based deep learning application capable of objectively quantifying tooth plaque in fluorescence images by calculating the plaque-tooth area ratio.

methodsA total of 2,490 fluorescence image of the Lingual surfaces of mandibular anterior teeth from 498 participants were used to train and test a YOLO v11 model with optimized hyperparameters for detecting tooth and plaque. After the model was developed, 30 additional participants were recruited, and their fluorescence image were evaluated for clinical validation by calculating the plaque-tooth area ratio. A web application was developed for clinical use, and validation compared AI predictions with clinical ratings via intraclass correlation coefficient analysis.

resultsThe deep learning model accurately detected and segmented teeth and dental plaque, with F1 scores of 0.81 for both tasks. Mean average precision at an intersection over union threshold of 0.50 (mAP50) was 0.83 and 0.84, respectively. The model achieved average precision scores of 0.969 for teeth and 0.706 for plaque, with an overall mAP50 of 0.838. Clinical validation showed strong agreement with expert assessments (ICC = 0.947) and a 97.9% reduction in evaluation time.

conclusionsThe web application demonstrated high accuracy in identifying and quantifying tooth plaque objectively in fluorescence images, supporting its potential as an oral hygiene assessment tool for the prevention of periodontal disease. CLINICAL SIGNIFICANCE: This deep learning-based web application offers an effective, and objectively scalable solution for dental plaque quantification, enhancing diagnostic precision and supporting timely periodontal intervention. Its integration into clinical workflows might improve treatment planning, promote patient compliance, and enable standardised monitoring of oral hygiene status, ultimately contributing to improved periodontal outcomes.

Indexed as

Deep LearningDental PlaqueOptical ImagingAdultFemaleHumansMaleMiddle AgedAutomated quantificationDeep learningDental plaqueFluorescence imagesWeb application

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.