Evidence map›Paper›PMID 40956326›Full record

ReviewArchives of microbiology2025

Cyanobacterial scytonemin, a potential photoprotective natural pigment: biomedical, industrial and environmental applications.

Akshaya Kumar Behera, Sudhamayee Parida, Amiya Kumar Mandal, Srimanta Patra, Mrutyunjay Jena

Abstract readReview
PubMed Publisher
In one paragraph

Review in Archives of microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Akshaya Kumar BeheraAlgal Biotechnology and Molecular Systematic Laboratory, Post Graduate Department of Botany, Berhampur University, Bhanja Bihar, Berhampur, 760007, Odisha, India.
Sudhamayee ParidaAlgal Biotechnology and Molecular Systematic Laboratory, Post Graduate Department of Botany, Berhampur University, Bhanja Bihar, Berhampur, 760007, Odisha, India.
Amiya Kumar MandalAlgal Biotechnology and Molecular Systematic Laboratory, Post Graduate Department of Botany, Berhampur University, Bhanja Bihar, Berhampur, 760007, Odisha, India.
Srimanta PatraAlgal Biotechnology and Molecular Systematic Laboratory, Post Graduate Department of Botany, Berhampur University, Bhanja Bihar, Berhampur, 760007, Odisha, India.
Mrutyunjay JenaAlgal Biotechnology and Molecular Systematic Laboratory, Post Graduate Department of Botany, Berhampur University, Bhanja Bihar, Berhampur, 760007, Odisha, India. mrutyunjay.jena@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A pigment called scytonemin is produced by cyanobacteria under stress conditions. It is a lipid-soluble, yellow-brown indole-alkaloid pigment that is mostly found in the extracellular polysaccharide (EPS) sheaths or capsules of certain cyanobacteria. During radiation exposure, it has the potential to protect cyanobacteria from damaging UV rays due to its photoprotective properties. Because of its stability and durability, scytonemin is a good option for sunscreen compositions. Additionally, the antioxidant properties possessed by this compound help in scavenging reactive oxygen species, which is beneficial in creating medications to treat diseases linked to oxidative stress. Its stability makes it a promising biomarker for palaeoclimatological reconstructions and highlights its importance as a biosignature in astrobiology. Furthermore, its recently revealed anti-inflammatory and powerful antiproliferative capabilities, particularly the suppression of cell cycle-regulating kinases, make it an attractive pharmacophore for creating innovative therapies for hyperproliferative illnesses such as cancer. Its durability and distinct spectroscopic signal highlight its importance as a biosignature in astrobiology. Continued study into its biosynthesis, various functions, and scalable manufacturing methods is critical for its future commercialization and wider application in human welfare. This review discusses a brief overview of the biochemistry and biosynthesis of scytonemin, focusing on the biomedical, industrial, and environmental applications.

Indexed as

CyanobacteriaIndolesPhenolsPigments, BiologicalAntioxidantsHumansSunscreening AgentsUltraviolet RaysAntioxidantsIndolesPhenolsPigments, BiologicalscytoneminSunscreening AgentsAntioxidantCyanobacteriaPhotoprotectionRadiationScytoneminSecondary metabolite

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.