Evidence map›Paper›PMID 40956172›Full record

Trial reportInternational journal of surgery (London, England)2026

Tracheal intubation in the thyroid surgical position improves recurrent laryngeal nerve monitoring: a dual-center randomized trial.

Enci Liu, Junjie Qin, Xiaoyu Li, Yong Qi, Lingzhi Wang, Xianjiang Wu, Zhanbo Yi, Junping Chen, Bo Lu

Abstract readRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in International journal of surgery (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Enci LiuDepartment of Anaesthesiology, Ningbo No. 2 Hospital, Ningbo University and Hangzhou Medical College, Zhejiang Province, China.ORCID 0009-0003-6806-9696
Junjie QinDepartment of Anaesthesiology, Ningbo Medical Centre Lihuili Hospital, Ningbo, Zhejiang Province, China.ORCID 0009-0009-6923-4474
Xiaoyu LiDepartment of Anaesthesiology, Ningbo No. 2 Hospital, Ningbo University and Hangzhou Medical College, Zhejiang Province, China.ORCID 0000-0001-8209-3631
Yong QiDepartment of Anaesthesiology, Ningbo Medical Centre Lihuili Hospital, Ningbo, Zhejiang Province, China.
Lingzhi WangDepartment of Anaesthesiology, Ningbo Medical Centre Lihuili Hospital, Ningbo, Zhejiang Province, China.
Xianjiang WuDepartment of Thyroid Surgery, Ningbo No. 2 Hospital, Ningbo University and Hangzhou Medical College, Zhejiang Province, China.
Zhanbo YiDepartment of Thyroid Surgery, Ningbo No. 2 Hospital, Ningbo University and Hangzhou Medical College, Zhejiang Province, China.
Junping ChenDepartment of Anaesthesiology, Ningbo No. 2 Hospital, Ningbo University and Hangzhou Medical College, Zhejiang Province, China.
Bo LuDepartment of Anaesthesiology, Ningbo No. 2 Hospital, Ningbo University and Hangzhou Medical College, Zhejiang Province, China.ORCID 0000-0003-1815-6778

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntraoperative neuromonitoring (IONM) is a critical adjunct in thyroid surgery to preserve recurrent laryngeal nerve function. This study aims to evaluate whether tracheal intubation in the thyroid surgical position enhances IONM signal quality compared with the standard supine position.

methodsIn this dual-center, parallel-group, randomized trial, 184 adults scheduled for elective thyroidectomy requiring IONM were allocated 1:1 to intubation in either the thyroid surgical position or the conventional supine position. The modified intention-to-treat cohort comprised 167 participants (85 vs 82) with an assessable baseline vagus response (V1). The primary outcome was the incidence of satisfactory electromyography (EMG) signals, defined as an initial vagus nerve EMG amplitude exceeding 500 μV when stimulated at 1.0 mA. Secondary outcomes included EMG signal amplitude, intubation-related metrics (e.g., Cormack-Lehane grades, intubation difficulty scale scores, intubation time, and depth of intubation), postoperative complications (e.g., lip lesions, dental injury, postoperative nausea and vomiting, dizziness, and headache), and clinician satisfaction with patient positioning and mask ventilation.

resultsSatisfactory V1 signals occurred in 82/85 patients (96.47%) in the thyroid surgical position group versus 70/82 (85.37%) in the supine group (relative risk 1.13; 95% CI 1.03-1.24; P = 0.0145). Intubation time and Cormack-Lehane grades did not differ significantly, but the thyroid surgical position group required deeper EMG tube insertion (22 cm [21-23] vs 22 cm [21-22]; median differences 1, 95% CI 0-1; P = 0.046). Postoperative complications did not differ significantly between groups (all P > 0.05). Clinician satisfaction scores were significantly higher in the thyroid surgical position group (median 9 vs 5; median differences 4, 95% CI 3-4; P < 0.0001). Mask ventilation satisfaction was also rated higher in the thyroid surgical position group (median 9 vs 8; median differences 1, 95% CI 0-1 P < 0.0001).

conclusionsTracheal intubation in the thyroid surgical position significantly improves IONM signal quality and clinician satisfaction without increasing intubation difficulty or postoperative complications. Adopting this simple positioning strategy can optimize EMG tube placement and enhance the reliability of IONM during thyroid surgery.

Indexed as

Intubation, IntratrachealMonitoring, IntraoperativePatient PositioningRecurrent Laryngeal NerveRecurrent Laryngeal Nerve InjuriesThyroidectomyAdultAgedElectromyographyFemaleHumansMaleMiddle Agedelectromyographyintraoperative neuromonitoringrecurrent laryngeal nervethyroid surgerytracheal intubation

Identifiers

PMID40956172
PMCPMC12825681

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.