Evidence map›Paper›PMID 40956086›Full record

ArticleJournal of virology2025

Esther Shaffer, Guney Boso, Reza Sadjadpour, Venkat V S R K Yedavalli, Oscar Lam, Christine A Kozak

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Esther ShafferViral Biology Section, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.
Guney BosoDepartment of Biological Sciences, Salisbury University, Salisbury, Maryland, USA.
Reza SadjadpourViral Biology Section, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.
Venkat V S R K YedavalliViral Biology Section, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.
Oscar LamViral Biology Section, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.
Christine A KozakViral Biology Section, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.ORCID 0000-0001-5863-6915

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Apobec3 (A3, apolipoprotein B editing complex 3) is a cytidine deaminase with broadly antiretroviral activity. A3 is packaged in virions and converts cytidines to uracil (C > U) in viral minus-strand DNA during reverse transcription, resulting in guanosine to adenosine (G > A) mutations in the viral plus strand. Mouse Apobec3 (mA3) mutagenizes numerous infectious retroviruses and some families of endogenous retroviruses. Here we show that endogenous mouse mammary tumor viruses, termed

Indexed as

Cytidine DeaminaseEndogenous RetrovirusesEvolution, MolecularMammary Tumor Virus, MouseMutationAnimalsFemaleMiceMutagenesisProvirusesTerminal Repeat SequencesApobec3 protein, mouseCytidine Deaminaseadaptive evolution in miceApobec3 hypermutationmammary tumor virusesmouse Apobec3 evolution

Identifiers

PMID40956086
PMCPMC12548423

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.