In one paragraphArticle in Plant biotechnology journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
14 authors.
Houyin DengState Key Laboratory of Tree Genetics and Breeding, National Engineering Research Center of Tree Breeding and Ecological Restoration, Engineering Technology Research Center of Black Locust of National Forestry and Grassland Administration, College of Biological Sciences and Technology, Beijing Forestry University, Beijing, People's Republic of China.ORCID https://orcid.org/0009-0006-0343-1772 Ye ZhaoState Key Laboratory of Tree Genetics and Breeding, National Engineering Research Center of Tree Breeding and Ecological Restoration, Engineering Technology Research Center of Black Locust of National Forestry and Grassland Administration, College of Biological Sciences and Technology, Beijing Forestry University, Beijing, People's Republic of China.ORCID https://orcid.org/0000-0002-9325-0695 Jie LiuState Key Laboratory of Tree Genetics and Breeding, National Engineering Research Center of Tree Breeding and Ecological Restoration, Engineering Technology Research Center of Black Locust of National Forestry and Grassland Administration, College of Biological Sciences and Technology, Beijing Forestry University, Beijing, People's Republic of China.ORCID https://orcid.org/0000-0002-5029-4401 Kunjin HanState Key Laboratory of Tree Genetics and Breeding, National Engineering Research Center of Tree Breeding and Ecological Restoration, Engineering Technology Research Center of Black Locust of National Forestry and Grassland Administration, College of Biological Sciences and Technology, Beijing Forestry University, Beijing, People's Republic of China.ORCID https://orcid.org/0009-0005-2253-5625 Juan HanState Key Laboratory of Tree Genetics and Breeding, National Engineering Research Center of Tree Breeding and Ecological Restoration, Engineering Technology Research Center of Black Locust of National Forestry and Grassland Administration, College of Biological Sciences and Technology, Beijing Forestry University, Beijing, People's Republic of China.ORCID https://orcid.org/0000-0002-3102-1176 Meng KeState Key Laboratory of Tree Genetics and Breeding, National Engineering Research Center of Tree Breeding and Ecological Restoration, Engineering Technology Research Center of Black Locust of National Forestry and Grassland Administration, College of Biological Sciences and Technology, Beijing Forestry University, Beijing, People's Republic of China.ORCID https://orcid.org/0009-0009-0338-1017 Yuhan SunState Key Laboratory of Tree Genetics and Breeding, National Engineering Research Center of Tree Breeding and Ecological Restoration, Engineering Technology Research Center of Black Locust of National Forestry and Grassland Administration, College of Biological Sciences and Technology, Beijing Forestry University, Beijing, People's Republic of China.ORCID https://orcid.org/0000-0001-5160-5075 Yun LiState Key Laboratory of Tree Genetics and Breeding, National Engineering Research Center of Tree Breeding and Ecological Restoration, Engineering Technology Research Center of Black Locust of National Forestry and Grassland Administration, College of Biological Sciences and Technology, Beijing Forestry University, Beijing, People's Republic of China.ORCID https://orcid.org/0000-0002-8426-565X Funding
Key-Area Research and Development Program of Guangdong Province 2020B020215001The National Key Research and Development Plan Project Sub-Subject 2022YFD2200201-6The National Natural Science Foundation of China 31972956
6 · The paper itselfAbstract
Selfing often causes inbreeding depression, especially during seed and seedling stages. However, some selfed progeny show low inbreeding depression with enhanced vigour, differing from inbred counterparts. This study investigates the molecular mechanisms maintaining seed vigour during selfing in Cunninghamia lanceolata. Evaluation showed that selfed seeds had medium vigour compared to other inbred and non-inbred seeds. Transcriptome analysis revealed similar gene expression patterns in the radicles and hypocotyls of inbred seeds. GO enrichment analysis identified adenine salvage as a key pathway related to seed vigour in selfed seeds. Purine metabolites (AMP, ADP, ATP) were higher in inbred seeds with better vigour, correlating with increased APRT enzyme activity. APRT inhibition by 6-diaminopurine had varying effects: high-vigour seeds were significantly inhibited, low-vigour seeds showed weaker inhibition, and selfed seeds exhibited an intermediate response. The addition of adenine and AMP partially restored seed vigour, further supporting the role of adenine salvage in vigour maintenance. A significant positive correlation (r > 0.922, p < 0.0001) between ClAPRT3 expression and APRT activity suggests that ClAPRT3 reflects APRT activity. Consistently, ClAPRT3 overexpression in Arabidopsis thaliana significantly enhanced radicle and hypocotyl length. Although ClMYB23 negatively regulates ClAPRT3 expression, no mutation was detected in the MYB binding motif among inbred progeny. Instead, variations in the ClAPRT3 coding sequence led to differences in binding energy with its ligand, which may partially explain the observed differences in APRT activity. These findings provide insights into the transcriptional and metabolic regulation of adenine salvage in maintaining seed vigour under inbreeding.
Indexed as
AdenineAdenine PhosphoribosyltransferasePlant ProteinsPurinesSeedsGene Expression Regulation, PlantAdenineAdenine PhosphoribosyltransferasePlant ProteinsPurinesadenine phosphoribosyl transferaseadenine salvageCunninghamia lanceolatapurine metabolitesseed vigourselfing
Identifiers
PMID40956007
PMCPMC12906808
What OpenQuestion holds
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LicenceCC BY
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