Evidence map›Paper›PMID 40955847›Full record

ArticleIntegrative cancer therapies

Effectiveness and Safety of Nasal Herbal Steam Therapy for Post-Extubation Respiratory Symptoms: A Methodology of Pragmatic Randomized Controlled, Parallel Grouped Study.

Sung-Eun Hong, Myung Han Hyun, Sang Hyung Lee, Bup-Woo Kim, Hee Jun Kim, Eun Ju Ko, Jee Young Lee

Abstract read
In one paragraph

Article in Integrative cancer therapies. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sung-Eun HongIntegrative Cancer Center, CHA Ilsan Medical Center, CHA University School of Medicine, Goyang-si, Gyeonggi-do, Rep of Korea.ORCID 0000-0002-7505-8309
Myung Han HyunIntegrative Cancer Center, CHA Ilsan Medical Center, CHA University School of Medicine, Goyang-si, Gyeonggi-do, Rep of Korea.ORCID 0000-0003-4228-5676
Sang Hyung LeeIntegrative Cancer Center, CHA Ilsan Medical Center, CHA University School of Medicine, Goyang-si, Gyeonggi-do, Rep of Korea.ORCID 0009-0001-5708-9638
Bup-Woo KimDepartment of Surgery, CHA Ilsan Medical Center, CHA University School of Medicine, Goyang-si, Gyeonggi-do, Rep of Korea.ORCID 0000-0002-1342-9055
Hee Jun KimDepartment of Surgery, CHA Ilsan Medical Center, CHA University School of Medicine, Goyang-si, Gyeonggi-do, Rep of Korea.ORCID 0000-0001-6549-381X
Eun Ju KoIntegrative Cancer Center, CHA Ilsan Medical Center, CHA University School of Medicine, Goyang-si, Gyeonggi-do, Rep of Korea.
Jee Young LeeIntegrative Cancer Center, CHA Ilsan Medical Center, CHA University School of Medicine, Goyang-si, Gyeonggi-do, Rep of Korea.ORCID 0000-0002-1080-1915

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-extubastion respiratory symptoms (PERS) are a common sequelae of endotracheal intubation, impeding postoperative recovery. Despite the widespread use of prophylactic corticosteroids and symptomatic management, these approaches have limitations in alleviating PERS. In this study, we aim to evaluate the efficacy and safety of nasal herbal steam therapy (NHST), a traditional Korean medicine intervention, in managing PERS among patients with thyroid cancer following endotracheal intubation. In this pragmatic, parallel-group randomized controlled trial, 66 post-thyroidectomy patients with thyroid cancer who underwent endotracheal intubation will be randomly assigned in a 1:1 ratio to either the NHST group or the standard care group. The intervention group will receive personalized NHST for 5 consecutive days, whereas the control group will follow conventional postoperative care protocols. The primary endpoint is the change in Wisconsin Upper Respiratory Symptom Survey scores from baseline to day 5. Secondary endpoints included patient-reported symptom relief, safety assessments, and adherence rates. By investigating the therapeutic potential of NHST, this study will establish its role as a non-invasive, adjunctive intervention for improving intubation-related complications, potentially contributing to broadening integrative treatment strategies and optimizing recovery outcomes for patients with PERS. The study will be conducted in accordance with the Declaration of Helsinki and approved by the Institutional Review Board of CHA Ilsan Medical Center (ICHA 2024-011-006, date of approval 2024-09-04).

Indexed as

Airway ExtubationPostoperative ComplicationsAdultFemaleHumansIntubation, IntratrachealMaleMedicine, Korean TraditionalMiddle AgedPragmatic Clinical Trials as TopicRandomized Controlled Trials as TopicSteamThyroidectomyThyroid NeoplasmsTreatment OutcomeSteamintubation-related complicationsnasal steam therapypost-extubation respiratory symptomsWisconsin upper respiratory symptom survey

Identifiers

PMID40955847
PMCPMC12441290

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.