Evidence map›Paper›PMID 40955826›Full record

ArticleBiomaterials science2025

Dual-action prevention of adherent and non-adherent biofouling

Grace H Nguyen, Aasma Sapkota, Elizabeth J Brisbois

Abstract read
In one paragraph

Article in Biomaterials science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Grace H NguyenSchool of Chemical, Materials, and Biomedical Engineering, University of Georgia, Athens, GA, 30602, USA. ejbrisbois@uga.edu.
Aasma SapkotaSchool of Chemical, Materials, and Biomedical Engineering, University of Georgia, Athens, GA, 30602, USA. ejbrisbois@uga.edu.
Elizabeth J BrisboisSchool of Chemical, Materials, and Biomedical Engineering, University of Georgia, Athens, GA, 30602, USA. ejbrisbois@uga.edu.ORCID http://orcid.org/0000-0002-9283-5448

Funding

Bioinspired antifouling and thromboresistant polymers for blood-contacting interfacesR01HL151473 · NHLBI · UNIVERSITY OF GEORGIA · PI BRISBOIS, ELIZABETH JOY · 2020 to 2023
$1.4M
NHLBI NIH HHS R01 HL151473
6 · The paper itself

Abstract

Contemporary clinical problems, such as medical device failure due to onset infection and thrombosis, pose a significant threat to the care and treatment of critical patients. While infection is typically treated with broad-spectrum antibiotics, and thrombosis is treated with systemic administration of anticoagulants, these options are less favorable because of the escalation of antibiotic resistance and adverse anticoagulation effects such as excessive bleeding and platelet consumption. Alternative strategies must be considered to address these issues before the current strategies become ineffective and cause irreversible damage. One such strategy is the combination of a bioactive therapeutic, nitric oxide (NO), with a passive anti-fouling technique, slippery nanoemulsion-infused porous surfaces (SNIPS). Loading the NO donor

Indexed as

Anti-Bacterial AgentsBiofoulingNitric OxideNitric Oxide DonorsS-NitrosoglutathioneAnimalsBacterial AdhesionEmulsionsEscherichia coliHumansPorosityStaphylococcus aureusSurface PropertiesAnti-Bacterial AgentsEmulsionsNitric OxideNitric Oxide DonorsS-Nitrosoglutathione

Identifiers

PMID40955826
PMCPMC12439328

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.