ArticlePediatric pulmonology2025
Detecting Impaired Lung Growth Using the Conditional Change Score of FEV
Article in Pediatric pulmonology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Detecting Impaired Lung Growth Using the Conditional Change Score of FEVPediatric pulmonology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundIt has been suggested that a quarter of children with asthma show impaired lung growth, with better initial function as a risk factor. A conditional change score (CCS) for FEV
objectiveTo evaluate whether the use of the CCS allows the identification of a subgroup of children with asthma that has an impaired lung growth, and to identify the risk factors of impaired growth.
methodsWe reanalyzed the data of 295 children with confirmed asthma (199 boys) who had undergone at least 10 spirometry tests from the age of 8 who were selected from a single-center open cohort. The annualized rate of change (slope) for prebronchodilator FEV
resultsIn total, 46 children (16%, 95% confidence interval: 12-20) followed up for a median duration of 6.5 years [interquartile: 5.7-7.3] exhibited an impaired lung growth. The CCS correlated with the standard deviation of individual slopes (FEV
conclusionWe confirm that some children with asthma (16%) show impaired lung growth with better initial lung function and decreased FEV
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.