ArticleNanoscale horizons2025
Proline stabilizes amphiphilic gold nanoparticles
Article in Nanoscale horizons, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Direct Measurement of Protein Pair Interaction Potential.ACS nano · 2026Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Colloidal dispersions are key in many fields of science and technology. Recently, we have shown that small molecules can stabilize dispersions of nanoscale objects, such as proteins and nanoparticles by screening their net attractive interactions. This new effect is essentially the opposite of the well-known salt screening of electrostatic interaction. Here we show that small molecule stabilization of nanoparticles is a phenomenon strongly linked to the hydrophobic content of the particles as well as to the strength of their hydrophobic attraction. We compare the effect of proline on gold nanoparticles coated with 11-mercaptoundecane sulfonate (MUS) at varying percentages of the hydrophobic ligand octanethiol (OT). We show that the larger the percentage of OT, the larger the proline stabilization effect is. We also compare the effect of proline on water dispersions of nanoparticles with that on heavy water dispersions. In the latter, the hydrophobic effect plays a bigger role. We find that in D
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Registered trials
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