ArticlePacing and clinical electrophysiology : PACE2025
Initial Experience With Implantation Left Bundle Branch Pacing Leads Without a Dedicated Three-Dimensional Sheath.
Article in Pacing and clinical electrophysiology : PACE, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Initial Experience With Implantation Left Bundle Branch Pacing Leads Without a Dedicated Three-Dimensional Sheath.Pacing and clinical electrophysiology : PACE · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsLeft bundle branch area pacing (LBBAP) has emerged as an alternative to cardiac stimulation via right ventricular pacing and cardiac resynchronization therapy using coronary sinus leads. The approach utilizes dedicated three-dimensional guiding catheters for lead placement. Our objective was to evaluate the feasibility and safety of a simplified approach of implantation of an LBBAP electrode without a dedicated guiding catheter.
methodsThis was a prospective single-center proof-of-concept evaluation. Patients with an indication for dual-chamber pacemaker implantation were consecutively enrolled. All patients received ventricular lead placement with a commercially available stylet-driven pacemaker lead. LBBAP was attempted without the use of a dedicated guiding catheter but with the help of a manually three-dimensionally pre-curved stylet.
resultsA total of 24 patients were analyzed. Procedure and fluoroscopy durations were 61 ± 12 min and 7.4 ± 3.9 min, while LBBAP lead placement was successful in 19 patients (79%). In these patients, the V6-R-wave peak time was 74 ± 11 ms, the V1V6 interpeak interval was 51 ± 11 ms, and QRS width during unipolar stimulation was 123 ± 14 ms. No complications attributed to the transseptal route of the pacing lead occurred. After a mean follow-up of 104 ± 20 days, there was no significant change in QRS widths (123 ± 15 ms, p = 0.94), V6-R wave peak time (70 ± 11 ms, p = 0.3), and V1V6 interpeak interval (45 ± 10 ms; p = 0.12).
conclusionImplantation of an LBBAP electrode without the use of a dedicated three-dimensional sheath is feasible and safe in a high proportion of patients. Further studies are necessary to define the impact of this technique for potential use in clinical routine.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.