Evidence map›Paper›PMID 40955650›Full record

ReviewPacing and clinical electrophysiology : PACE2025

Expected Benefits From Antibacterial Envelope in Different CIED Patient Populations.

David Duncker, Christine Alonso, Mauro Biffi, Francisco Costa, Rim El Bouazzaoui, Panagiota Flevari, Maria Hee Jung Park Frausing, Andreas Goette, Didier Klug, Edward Maclean and 6 more

Abstract readReview
In one paragraph

Review in Pacing and clinical electrophysiology : PACE, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Preclinical evaluation of a compliant and absorbable cardiac implantable electronic device antibacterial envelope.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

David DunckerDepartment of Cardiology and Angiology, Hannover Heart Rhythm Center, Hannover Medical School, Hannover, Germany.
Christine AlonsoGHP Ambroise Paré-Hartman, Neuilly sur Seine, France.
Mauro BiffiInstitute of Cardiology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Francisco CostaHospital da Luz, SA, Lisbon, Portugal.
Rim El BouazzaouiCentre Hospitalier Libourne, Libourne, France.
Panagiota FlevariAttikon University Hospital, Athens, Greece.
Maria Hee Jung Park FrausingAarhus University Hospital, Aarhus, Denmark.
Andreas GoetteSt. Vincenz Hospital, Paderborn, Germany and MAESTRIA Consortium/AFNET, Münster, Germany.
Didier KlugUniversity of Lille, Lille, France.
Edward MacleanBartholomew's Hospital, London, UK.
Tobias TönnisUniversity Heart and Vascular Center, Hamburg, Germany.
Emilce TruccoHospital Universitari de Girona Dr Josep Trueta, Girona, Spain.
Andrew J TurleyJames Cook University Hospital, Middlesbrough, UK.
Jay WrightLiverpool Heart and Chest Hospital, Liverpool, UK.
Bruno ValenteCentro Hospitalar Universitário de Lisboa Central, Lisbon, Portugal.
Matteo ZiacchiInstitute of Cardiology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.

Funding

Medtronic Inc
6 · The paper itself

Abstract

Antibacterial envelope has proven to be safe and effective in reducing cardiac implantable electronic device (CIED) infection. Recently, its role in pocket healing process has also started to be studied, showing additional potential benefits for the patients. Risk scores such as the PADIT and the BLISTER ones have been developed to stratify patients at higher risk of developing CIED infections, but their use is still limited. There is a need for clear and concise practical guidance and scores for the correct stratification of patients at risk to develop CIED infections, to apply an effective preventive strategy. This article examines the most recent findings on the effectiveness of antibacterial envelopes in preventing CIED infections and introduces the latest concept of pocket stabilization. Additionally, patient populations that could potentially benefit from antibacterial envelope for both indications are provided based on the agreement of an expert panel made up of 16 European electrophysiologists from high-volume centers. Future studies will have to evaluate the strength of those proposals and the benefits of pocket stabilization in the long-term.

Indexed as

Anti-Bacterial AgentsAntibiotic ProphylaxisDefibrillators, ImplantablePacemaker, ArtificialProsthesis-Related InfectionsHumansTreatment OutcomeAnti-Bacterial Agentsantibacterial envelopeCIED implantationCIED infectionpocket healing

Identifiers

PMID40955650
PMCPMC12594273

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.