Evidence map›Paper›PMID 40955560›Full record

ArticleHypertension (Dallas, Tex. : 1979)2025

Expected Impact of Implementing the PAHO Regional Sodium Targets in Mexico.

Karla Muciño-Sandoval, Rodrigo Zepeda-Tello, Nancy López-Olmedo, Dalia Stern, Lizbeth Tolentino-Mayo, Jorge Vargas-Meza, Kamara Pather, Josiemer Mattei, Juan A Rivera, Ismael Campos-Nonato and 2 more

Abstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Karla Muciño-SandovalCenter for Population Health Research (K.M.-S., N.L.-O., D.S., J.A.R., T.B.-G., A.B.-A.), National Institute of Public Health, Cuernavaca, Mexico.ORCID 0000-0002-0887-5595
Rodrigo Zepeda-TelloDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY (R.Z.-T.).ORCID 0000-0003-4471-5270
Nancy López-OlmedoCenter for Population Health Research (K.M.-S., N.L.-O., D.S., J.A.R., T.B.-G., A.B.-A.), National Institute of Public Health, Cuernavaca, Mexico.ORCID 0000-0002-7528-0954
Dalia SternCenter for Population Health Research (K.M.-S., N.L.-O., D.S., J.A.R., T.B.-G., A.B.-A.), National Institute of Public Health, Cuernavaca, Mexico.ORCID 0000-0003-3779-6543
Lizbeth Tolentino-MayoCenter for Nutrition and Health Research (L.T.-M., J.V.-M., I.C.-N.), National Institute of Public Health, Cuernavaca, Mexico.
Jorge Vargas-MezaCenter for Nutrition and Health Research (L.T.-M., J.V.-M., I.C.-N.), National Institute of Public Health, Cuernavaca, Mexico.
Kamara PatherUniversity of Sydney, Australia (K.P.).ORCID 0009-0004-7747-9053
Josiemer MatteiDepartment of Nutrition, Harvard T. H. Chan School of Public Health, Boston, MA (J.M.).ORCID 0000-0001-5424-8245
Juan A RiveraCenter for Population Health Research (K.M.-S., N.L.-O., D.S., J.A.R., T.B.-G., A.B.-A.), National Institute of Public Health, Cuernavaca, Mexico.ORCID 0000-0003-2586-4908
Ismael Campos-NonatoCenter for Nutrition and Health Research (L.T.-M., J.V.-M., I.C.-N.), National Institute of Public Health, Cuernavaca, Mexico.ORCID 0000-0001-5939-3396
Tonatiuh Barrientos-GutierrezCenter for Population Health Research (K.M.-S., N.L.-O., D.S., J.A.R., T.B.-G., A.B.-A.), National Institute of Public Health, Cuernavaca, Mexico.ORCID 0000-0002-0826-9106
Ana Basto-AbreuCenter for Population Health Research (K.M.-S., N.L.-O., D.S., J.A.R., T.B.-G., A.B.-A.), National Institute of Public Health, Cuernavaca, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExcessive sodium intake increases the risk of cardiovascular disease. Mexico has implemented voluntary measures to reduce sodium intake, but they are insufficient to meet the global target of sodium intake reduction by 2025. We aimed to simulate the expected impact of implementing the Pan American Health Organization Sodium Targets in processed and ultra-processed foods in Mexico.

methodsSodium consumption was estimated using 24-hour dietary recall data from the 2016 Mexican National Health and Nutrition Survey. The intervention consisted of implementing Pan American Health Organization Sodium Targets in 16 food groups divided into 75 subgroups. We estimated the potential decrease in systolic blood pressure using a linear function by age and hypertension status, and the potential decrease in deaths and incident cases of cardiovascular disease, chronic kidney disease, and stomach cancer using a nonparametric version of the potential impact fraction.

resultsImplementing the Pan American Health Organization Sodium Targets could reduce overall sodium consumption by 25%, leading to a 1.2 mm Hg reduction in systolic blood pressure (2.1 mm Hg in people with hypertension). Annually, this intervention could prevent 5.3% of deaths (12 866 in 2019) and 3.9% of incident cases (43 940 in 2019) of cardiovascular disease, chronic kidney disease and stomach cancer.

conclusionsImplementing the Pan American Health Organization Sodium Targets is expected to reduce sodium consumption and improve cardiovascular-related outcomes. Interventions in real-life settings, testing this premise should consider barriers and facilitators for implementation and maintenance, considering consumer preferences and fluctuations in food content.

Indexed as

Cardiovascular DiseasesHypertensionSodium, DietaryAdultAgedBlood PressureFemaleHumansMaleMexicoMiddle AgedNutrition SurveysRenal Insufficiency, ChronicSodium, Dietaryblood pressurecardiovascular diseasesMexiconutrition surveyspolicy makingsodium

Identifiers

PMID40955560
PMCPMC12529991

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.