ArticleJAMA neurology2025
Revised Diagnostic Criteria for Vascular Cognitive Impairment and Dementia-The VasCog-2-WSO Criteria.
Abstract read
In one paragraph
Article in JAMA neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed.
- Systemic Extracerebral Atherosclerotic Burden and Dementia Risk After Incident Stroke.Annals of clinical and translational neurology · 2026Article
- Assessing Microstructural and Molecular Brain Changes in Early Cognitive Decline Using Multiparametric 3T Magnetic Resonance Imaging.Neurology international · 2026Article
- Validation of the VasCog-2-WSO VCID Criteria in a Dementia-Free and Stroke-Free Community Cohort: Cardiovascular Risk and Mortality.Neurology · 2026Article
- Cerebral small vessel disease: pearls and pitfalls from unexplored risk factors to treatment.Arquivos de neuro-psiquiatria · 2026Review
- Major Adverse Cognitive Events (MACE-Cog): A New "MACE" Framework for Cognitive Outcomes in Cardiovascular Diseases and Stroke.Circulation · 2026Review
- Neuro-Renal Crosstalk Across the Chronic Kidney Disease Spectrum: Stage-Dependent Molecular Mechanisms of Cognitive Impairment-An Integrative Review.International journal of molecular sciences · 2026Review
- Functional Connectome Predicts Cognition and Links White Matter Hyperintensity Burden to Cognitive Impairment Across the Vascular Cognitive Impairment Continuum.Brain sciences · 2026Article
- Clinical Characteristics and Influencing Factors of Depressive Symptoms in Patients With Vascular Cognitive Impairment.Actas espanolas de psiquiatria · 2026Observational
- Visual Hallucinations and Cognitive Impairment as the Initial Presentation of Severe Hypothyroidism in an Elderly Patient: A Case Report.Geriatrics (Basel, Switzerland) · 2026Article
- Electroacupuncture Ameliorates Cognitive Impairment in Vascular Dementia Rats: Potential Involvement of the Astrocyte-Synapse Axis.Brain and behavior · 2026Article
- Development and validation of a Cog-Free risk predicting tool for dementia in a community setting.General psychiatry · 2026Article
- Operationalizing diffusion magnetic resonance imaging positivity for detection of vascular contributions to impairment and dementia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Transcriptomic Evidence of MAS1 Receptor Dysregulation and a Failed Compensatory State in Human Vascular Cognitive Impairment.medRxiv : the preprint server for health sciences · 2026Article
- Quality and reliability of vascular cognitive impairment-related information on Chinese social media platforms.Medicine · 2026Article
- Association of coronary artery bypass with cognitive impairment in coronary artery disease across APO (ε) genotypes in AllofUS.medRxiv : the preprint server for health sciences · 2026Article
- Beneficial Effects of Olive Oil and the Mediterranean Diet on Alzheimer's Disease and Vascular Dementia: A Review.Medicina (Kaunas, Lithuania) · 2026Review
- Associations between cognitive frailty and circulating cardiovascular biomarkers in a memory clinic cohort.GeroScience · 2026Article
- Vascular contribution to cognitive impairment and dementia (VCID): proceedings of 2025 workshop of the Jackson Laboratory.Mammalian genome : official journal of the International Mammalian Genome Society · 2026Article
- ESO annual stroke evidence update 2025.European stroke journal · 2026Review
- From Cerebrovascular Injury to Vascular Cognitive Impairment and Dementia: Therapeutic Potential of Stem Cell-Derived Extracellular Vesicles.Biomedicines · 2026Review
Corrections and comments
- Commented on by
Authors and funding
63 authors.
VasCog-2-WSO Criteria Consortium
Perminder S SachdevCentre for Healthy Brain Ageing, School of Clinical Medicine, University of New South Wales, Sydney, New South Wales, Australia.
Adam C BentvelzenCentre for Healthy Brain Ageing, School of Clinical Medicine, University of New South Wales, Sydney, New South Wales, Australia.
Nicole A KochanCentre for Healthy Brain Ageing, School of Clinical Medicine, University of New South Wales, Sydney, New South Wales, Australia.
Jiyang JiangCentre for Healthy Brain Ageing, School of Clinical Medicine, University of New South Wales, Sydney, New South Wales, Australia.
Satoshi HosokiCentre for Healthy Brain Ageing, School of Clinical Medicine, University of New South Wales, Sydney, New South Wales, Australia.
Rebecca KonczCentre for Healthy Brain Ageing, School of Clinical Medicine, University of New South Wales, Sydney, New South Wales, Australia.
Russell J ChanderCentre for Healthy Brain Ageing, School of Clinical Medicine, University of New South Wales, Sydney, New South Wales, Australia.
Danit SaksCentre for Healthy Brain Ageing, School of Clinical Medicine, University of New South Wales, Sydney, New South Wales, Australia.
Hugo P AbenDepartment of Neurology, Elisabeth TweeSteden Hospital, Tilburg, the Netherlands.
Daisy AcostaUniversidad Nacional Pedro Henriquez Urena, Santo Domingo, Dominican Republic.
Pia AndersenTheme Inflammation and Aging, Karolinska University Hospital, Stockholm, Sweden.
Frédéric AssalCognitive Neurology Unit, Faculty of Medicine, Geneva University Hospitals, Geneva, Switzerland.
Hee-Joon BaeDepartment of Neurology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seoul, South Korea.
Geert Jan BiesselsDepartment of Neurology, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, the Netherlands.
Deborah BlackerDepartment of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston.
Régis BordetUniv Lille, Inserm, CHU Lille, Lille Neuroscience & Cognition, Lille, France.
Emily M BricenoDepartment of Physical Medicine and Rehabilitation, University of Michigan Medical School, Ann Arbor.
Henry BrodatyCentre for Healthy Brain Ageing, School of Clinical Medicine, University of New South Wales, Sydney, New South Wales, Australia.
Amy BrodtmannCognitive Health Initiative, School of Translational Medicine, Monash University, Melbourne, Victoria, Australia.
Paulo CaramelliBehavioral and Cognitive Neurology Unit, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Erico Castro-CostaCenter for Studies in Public Health and Aging, Belo Horizonte, Brazil.
Hugues ChabriatCentre Neurovasculaire Translationnel-CERVCO and Département de Neurologie, Hopital Lariboisiere, APHP, Université Paris-Cité and Brain Institute, Paris, France.
Christopher ChenMemory Aging and Cognition Centre, Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Una ClancyCentre for Clinical Brain Sciences, UK Dementia Institute Centre, University of Edinburgh, Edinburgh, United Kingdom.
Lucette CysiqueThe Kirby Institute, University of New South Wales, Sydney, New South Wales, Australia.
Charles DeCarliAlzheimer's Disease Research Center, Department of Neurology, University of California, Davis, Sacramento, California.
Ding DingInstitute of Neurology, Fudan University Huashan Hospital, Shanghai, China.
Marco DueringMedical Image Analysis Center, Basel, Switzerland.
Eliasz EngelhardtInstituto de Neurologia Deolindo Couto, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Serge GauthierDepartment of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada.
Fatemeh GeranmayehDepartment of Brain Sciences, Imperial College London, London, United Kingdom.
Olivier GodefroyDepartment of Neurology, Amiens University Hospital, Amiens, France.
Philip GorelickSection of Vascular Neurology, Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Steven M GreenbergDepartment of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston.
Vesna JelicDivision of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden.
Hanna JokinenDivision of Neuropsychology, Neurocenter, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Raj N KalariaTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Murali KrishnaCentre for Health Systems Research, Institute of Public Health, Bangalore, India.
Kurt LancasterAlcohol and Drug Service, St Vincent's Hospital, Sydney, New South Wales, Australia.
Frank-Erik de LeeuwDepartment of Neurology, Research Institute for Medical Innovation, Radboudum and Donders Institute Brain, Cognition & Behaviour, Nijmegen, the Netherlands.
Jae-Sung LimDepartment of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Anna MarsegliaDivision of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden.
Javier Marta-MorenoNeurovascular Unit, Department of Neurology, Hospital Universitario Miguel Servet, Instituto Investigación Sanitaria- IIS Aragón, Zaragoza, Spain.
John T O'BrienDepartment of Psychiatry, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.
Leonardo PantoniDepartment of Biomedical and Clinical Sciences, University of Milan, Milan, Italy.
Matthew P PaseSchool of Psychological Science, Monash University, Melbourne, Victoria, Australia.
Sarah T PendleburyWolfson Building, Wolfson Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom.
Gary RosenbergCenter for Memory and Aging, University of New Mexico Health Sciences Center, Albuquerque.
Behnam SabayanHennepin Healthcare Research Institute, Department of Neurology, Hennepin County Medical Center, Minneapolis, Minnesota.
Emilia SalvadoriDepartment of Biomedical and Clinical Sciences, University of Milan, Milan, Italy.
Katherine SamarasClinical Obesity, Nutrition and Adipose Biology Laboratory, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia.
Ivy Anne SebastianDepartment of Neurology, Christian Medical College and Hospital, Ludhiana, Punjab, India.
Sudha SeshadriGlenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Science Center, San Antonio.
Eric E SmithDepartment of Clinical Neurosciences and Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada.
Velandai SrikanthNational Centre for Healthy Ageing, Melbourne, Victoria, Australia.
Kathryn StokesNeuropsychology and Cognitive Health, Baycrest Health Sciences Centre, Canada.
Felipe Kenji SudoD'Or Institute for Research and Education, Rio de Janeiro, Brazil.
Lukas SveikataCognitive Neurology Unit, Faculty of Medicine, Geneva University Hospitals, Geneva, Switzerland.
Michael ValenzuelaCentre for Healthy Brain Ageing, School of Clinical Medicine, University of New South Wales, Sydney, New South Wales, Australia.
Anders WallinInstitute of Neuroscience and Physiology at Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Joanna M WardlawCentre for Clinical Brain Sciences, UK Dementia Institute Centre, University of Edinburgh, Edinburgh, United Kingdom.
Qun XuHealth Management Center, Department of Neurology, Renji Hospital of Shanghai Jiaotong University School of Medicine, Shanghai, China.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Importance: Several sets of diagnostic criteria have been proposed for vascular cognitive impairment and dementia (VCID). The International Society for Vascular Behavioural and Cognitive Disorders (VasCog) working group published comprehensive operationalized criteria in 2014. Considering subsequent advances in the field, a revision was needed. Objective: To update the VasCog criteria to achieve consensus on diagnosis of VCID. Design, Setting, and Participants: VasCog criteria and other published diagnostic guidelines, aided by literature review of recent developments in VCID, were used as reference points for an online Delphi survey (minimum 3 rounds, ≥75% threshold for agreement), including operationalization of criteria and guidance on potential biomarkers. Seventy international experts from diverse international regions were invited to participate in 2023. Results: Three survey rounds included 49 to 54 participants that agreed on VasCog-2 diagnostic criteria for preclinical, mild, and major dementia levels of vascular cognitive impairment (under the overarching term VCID). Research guidelines, including the use of novel neuroimaging and fluid biomarkers, were also agreed on. The World Stroke Organization (WSO) endorsed the criteria, hence named VasCog-2-WSO. Conclusions and Relevance: The VasCog-2-WSO criteria update the VasCog criteria for the diagnosis of VCID, providing operationalization and additional guidance on potential neuroimaging and fluid biomarkers. VasCog-2-WSO should provide an international standard for VCID diagnosis, facilitating diagnostic consistency among clinicians and researchers.
Indexed as
Cognitive DysfunctionDementia, VascularBiomarkersConsensusDelphi TechniqueHumansBiomarkers
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.