ArticleJournal of multimorbidity and comorbidity
Exploring the association between BPPV, hypothyroidism, and metabolic comorbidities: A retrospective case-control study.
Article in Journal of multimorbidity and comorbidity. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Diabetes Mellitus as a Risk Factor in Recurrent Vestibular Disorders: An Update.Audiology research · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background & Objective: Benign paroxysmal positional vertigo (BPPV) is a leading cause of vertigo and has been loosely associated with osteoporosis, vitamin D deficiency, and broader metabolic dysfunction. Emerging evidence suggests that BPPV may relate to systemic conditions beyond the vestibular system. However, limited research has explored whether individuals with BPPV have increased rates of hypothyroidism, diabetes mellitus (DM), hypertension (HTN), or osteoporosis. The objective of this study was to examine the association between BPPV and hypothyroidism, diabetes mellitus (DM), hypertension (HTN), and osteoporosis. Study Design & Setting: This study was a retrospective case-control study using patient records from a vestibular outpatient rehabilitation clinic in Florida, USA. Patients & Outcomes: Adults diagnosed with BPPV over a six-month period were included in the study. Control data was derived from the National Center for Health Statistics (NCHS). Binomial logistic regression was performed to calculate odds ratios (ORs). Results: A total of 140 individuals diagnosed with BPPV (98 female, 42 male) were analyzed. Patients with BPPV demonstrated statistically significant higher odds of hypothyroidism (OR 2.635, 95% CI 1.260-5.51) and diabetes mellitus (OR 2.28, 95% CI 1.09-4.76) compared to national estimates. No significant associations were found for hypertension or osteoporosis. Conclusion: An association exists between BPPV and both hypothyroidism and diabetes mellitus. These findings support the role of systemic metabolic and endocrine dysfunction in the pathophysiology of BPPV and highlight the potential clinical value of screening for relevant comorbidities. Further research is warranted.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.