Use of Indocyanine Green in Fluorescence-Guided Resection of Mesenchymal Hamartoma of the Liver: A Report of Two Cases.

Indocyanine green (ICG) is a fluorescent agent administered preoperatively to assist in real-time visualization of pathologic tissue during a variety of surgical procedures, including the resection of solid tumors. This series describes the clinical presentation, fluorescence-guided resection, and outcome of two pediatric cases of mesenchymal hamartoma of the liver (MHL), a rare benign hepatic tumor. Use of this agent is widely documented in the literature for the management of more common malignant and benign liver tumors, though reporting for MHL is scarce. It is the purpose of this case series to contribute to the growing understanding of ICG's utility for this rare tumor, illustrated in two pediatric patients. We present the cases of a 21-month-old male patient and an 18-month-old female patient, both presenting with large hepatic masses causing symptoms secondary to compression of neighboring structures, necessitating surgical removal. Fluorescence-guided surgery using ICG was implemented for the precision resection of both neoplasms. This report provides valuable insight into ICG implementation for MHL in two pediatric patients, outlining how the agent safely and effectively facilitated the resection of these neoplasms.