ArticleInternational journal of general medicine2025
The Prognostic Significance of Visceral Adiposity Indices in Conjunction with Plasma Trace Elements in Newly Diagnosed Crohn's Disease.
Article in International journal of general medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Exploring new animal models of ulcerative colitis: evaluating chemical and patient-derived microbial triggers to advance translational relevance.Laboratory animal research · 2026Article
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Authors and funding
12 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Purpose: Visceral adipose tissue (VAT) is integral to the pathology of Crohn's disease (CD). While trace element imbalances affect both adipose tissue function and CD progression, their interplay remains poorly characterized. This study aimed to examine whether trace element status affects CD outcomes and whether this relationship is moderated by visceral adiposity. Patients and Methods: The data were collected retrospectively based on a prospective cohort of 300 patients newly diagnosed with CD from July 2019 to June 2022. Baseline plasma trace element levels were assessed, and VAT was measured via computed tomography (CT) scans at the time of diagnosis. Logistic regression analyses were performed. Results: Lower zinc and magnesium levels predicted clinical outcomes including intestinal complications and surgery (OR = 0.51, Conclusion: Dysregulated trace element homeostasis at baseline independently predicts adverse clinical outcomes in CD. The intricate relationship between trace elements and VAT could influence disease progression, suggesting potential targets for personalized treatment.
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