Evidence map›Paper›PMID 40955265›Full record

ArticleCureus2025

Introduction of Exercise Therapy Using Hybrid Assistive Limb (HAL®) Lumbar Type for Diabetes Patients: A Pilot Study.

Tomokazu Abe, Kousei Miura, Tsuyoshi Saito, Naoki Kayanoma, Yuuma Furukawa, Yoshihiro Yasunaga, Masashi Yamazaki, Masataka Kusunoki

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Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Tomokazu AbeGraduate School of Medicine, Nagoya University, Nagoya, JPN.
Kousei MiuraDepartment of Orthopaedic Surgery, Institute of Medicine, University of Tsukuba, Tsukuba, JPN.
Tsuyoshi SaitoAkishima Clinic, Medical Corporation Oda-kai, Nagoya, JPN.
Naoki KayanomaNagoya Diabetes Exercise Therapy Center, Apollon Co. Ltd, Nagoya, JPN.
Yuuma FurukawaNagoya Diabetes Exercise Therapy Center, Apollon Co. Ltd., Nagoya, JPN.
Yoshihiro YasunagaResearch Devision, Cyberdyne Inc., Tsukuba, JPN.
Masashi YamazakiDepartment of Orthopaedic Surgery, Institute of Medicine, University of Tsukuba, Tsukuba, JPN.
Masataka KusunokiAkishima Clinic, Medical Corporation Oda-kai, Nagoya, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExercise therapy is essential for diabetes management, but adherence remains challenging for many patients. The hybrid assistive limb (HAL) lumbar type is a wearable robot that has shown effectiveness in various conditions, yet its application in diabetes patients has not been investigated.

objectiveTo evaluate the feasibility and safety of exercise therapy using the HAL lumbar type for patients with diabetes and to exploratorily investigate its effects on physical function and metabolic parameters.

methodsThis pilot, prospective, single-arm study included nine patients with diabetes (mean age: 69.00±13.23 years). Participants underwent an exercise program using the HAL lumbar type, consisting of eight sessions of 60 minutes each. The program included stretching, squatting, and walking exercises, performed 1-2 times per week, with the goal of completion within 4 to 8 weeks. The primary outcome was the Sit-To-Stand test (STS test). Secondary outcomes included changes in body weight, body mass index (BMI), and metabolic parameters.

resultsAll participants completed the intervention without adverse events. Significant improvements were observed in the STS test (15.86±3.87 to 10.43±2.27 seconds, p<0.005), body weight (72.68±15.73 to 70.71±15.15 kg, p<0.05), and lipid metabolism parameters including total cholesterol (200.11±32.85 to 182.67±21.45 mg/dL, p<0.05) and LDL cholesterol (114.00±28.51 to 101.56±24.52 mg/dL, p<0.005).

conclusionExercise therapy using the HAL lumbar type was safely implemented in diabetes patients and showed potential benefits in improving physical function and lipid metabolism. These findings suggest that HAL-assisted exercise therapy might be a promising new approach for diabetes management.

Indexed as

diabeteserrorless motor learning effectexercise therapyhybrid assistive limbwearable exoskeleton

Identifiers

PMID40955265
PMCPMC12433586

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.