Evidence map›Paper›PMID 40955255›Full record

ReviewCureus2025

Outcomes of Early Versus Delayed Definitive Surgical Intervention in Multisystem Trauma Patients: A Systematic Review of Timing Strategies in General Surgery Emergencies.

Mazin Osman, Khald Alhamoud Almatar, Fahad Almatar, Shahd A Awad, Hind K Mohamed, Mohamed K Abouelsadat, Othman T Alamodi, Gorashi Humida Ali Gorashi, Albina Mercy, Mawada Taha and 1 more

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mazin OsmanGeneral Surgery, British United Provident Association, Jeddah, SAU.
Khald Alhamoud AlmatarSurgery, Royal Liverpool University Hospital, Liverpool, GBR.
Fahad AlmatarGeneral Practice, Victoria Medical Group, North York, CAN.
Shahd A AwadGeneral Surgery, Farwaniya Hospital, Sabah Al Nasser, KWT.
Hind K MohamedPediatric Surgery, University of Benghazi, Benghazi, LBY.
Mohamed K AbouelsadatVascular Surgery, Royal Free Hospital, London, GBR.
Othman T AlamodiGeneral Practice, Fakeeh Care Group, Jeddah, SAU.
Gorashi Humida Ali GorashiAnatomy, University of Khartoum, Khartoum, SDN.
Albina MercyInternal Medicine, Davao Medical School Foundation Inc., Davao City, PHL.
Mawada TahaGeneral Surgery, The National Ribat University, Khartoum, SDN.
Manahil AwanSurgery, Liaquat National Hospital, Karachi, PAK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review explores how the timing of surgery affects outcomes in adults with multisystem trauma requiring general surgical or orthopedic procedures. A targeted search of PubMed and other major databases up to July 2025 identified six relevant studies, including four observational cohorts, one meta-analysis, and one narrative review, collectively covering 273,683 patients. Early definitive surgery, performed within 24-48 hours of admission, was associated with lower mortality rates, fewer respiratory complications, and shorter ICU and hospital stays compared to delayed interventions. One large study reported no significant mortality difference, highlighting the importance of preoperative stabilization and individualized care. Despite variability in study design and the definition of "early" surgery, current evidence suggests that early operative management in stable trauma patients, including abdominal trauma, offers meaningful benefits in reducing complications and improving recovery.

Indexed as

delayed surgeryearly surgical interventiongeneral surgery emergenciesmultisystem traumatrauma outcomes

Identifiers

PMID40955255
PMCPMC12433577

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.