ArticleColorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland2025
Long-term perineal wound healing and re-operation rates after proctectomy in patients with inflammatory bowel disease-A retrospective multicentre study.
Article in Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Essential Updates in the Surgical Management of Inflammatory Bowel Disease: Current Topics From 2024 to Mid-2026.Annals of gastroenterological surgery · 2026Review
- Long-term perineal wound healing and re-operation rates after proctectomy in patients with inflammatory bowel disease-A retrospective multicentre study.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsPerineal wound complications occur frequently after proctectomy in patients with inflammatory bowel disease (IBD), with persistent perineal wounds appearing in some patients. This study examines the surgical outcomes after proctectomy in patients with IBD in a contemporary setting, with primary perineal wound healing as the primary end-point.
methodsThis is a multicentre retrospective cohort study with five Swedish hospitals participating. Patients with IBD who had undergone proctectomy during the period of 2000-2019 were included. Two exposures of interest were analysed: type of IBD, either ulcerative colitis (UC) or Crohn's disease (CD), and indication for surgery. Perineal wound healing was assessed at 3, 6, 12, and 24 months postoperatively. Multilevel binomial regression with complementary log-log link function was used to estimate healing over discrete time intervals, and a separate analysis concerning fistulising disease and healing was conducted.
resultsIn total, 408 patients (57% males, 56% with UC) were included. Refractory proctitis was the most common indication for surgery in both UC (50%) and CD (38%) patients. The 2-year overall healing rate was 91%, with 95% in the UC group and 86% in the CD group. Patients with CD had a significantly slower adjusted healing rate (HR 0.67, 95% CI 0.53; 0.85). Anal fistulas as an indication for proctectomy showed significantly lower odds of healing over the entire period compared with proctitis (OR = 0.31, p = 0.036).
conclusionsPerineal wound morbidity with formation of chronic sinuses remains a problem after proctectomy in patients with IBD, primarily in patients with CD and especially those with anal fistulas.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.