Evidence map›Paper›PMID 40954423›Full record

ArticleClinical rheumatology2025

Multiple comorbidities and economic burden of hospitalized gout patients in Guangdong Province.

Jie Ren, Xuantao Yan, Shan Zeng, Jiajing Wu, Siman Cao, Yangxing Luo, Wenhao Zhang, Wei Hu, Xiaoliang Huang, Yi Zhou

Abstract read
In one paragraph

Article in Clinical rheumatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
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2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Jie RenDepartment of Rheumatology and Immunology, the First Affiliated Hospital, Jinan University, Guangzhou, Guangdong, China.ORCID http://orcid.org/0000-0002-4464-0574
Xuantao YanDepartment of Rheumatology and Immunology, the First Affiliated Hospital, Jinan University, Guangzhou, Guangdong, China.
Shan ZengDepartment of Rheumatology and Immunology, the First Affiliated Hospital, Jinan University, Guangzhou, Guangdong, China.
Jiajing WuDepartment of Rheumatology and Immunology, the First Affiliated Hospital, Jinan University, Guangzhou, Guangdong, China.
Siman CaoDepartment of Rheumatology and Immunology, the First Affiliated Hospital, Jinan University, Guangzhou, Guangdong, China.
Yangxing LuoPazhou Lab, Guangzhou, Guangdong, China.
Wenhao ZhangGuangdong Provincial Health Commission Affairs Center, Guangzhou, Guangdong, China.
Wei HuGuangdong Provincial Health Commission Affairs Center, Guangzhou, Guangdong, China.
Xiaoliang HuangGuangdong Provincial Health Commission Affairs Center, Guangzhou, Guangdong, China. 497946115@qq.com.
Yi ZhouDepartment of Rheumatology and Immunology, the First Affiliated Hospital, Jinan University, Guangzhou, Guangdong, China. zhou21yi@163.com.

Funding

the Basic and Applied Basic Research Projects of Guangzhou Basic Research Program 202102020046
6 · The paper itself

Abstract

introductionThis study aimed to analyze the prevalence of multiple comorbidities and economic burden of hospitalized patients with gout in Guangdong Province.

methodsWe retrieved the homepage information of 593,792 hospitalized patients with gout from January 1, 2015 to December 31, 2021 through the Guangdong Provincial Medical Record Homepage System and analyzed the prevalence of single comorbidity and multiple comorbidities and economic burden.

results1. The prevalence of gout was 1.31%. The prevalence in males was five times higher than that of females. 2. The prevalence of hypertension was highest (42.59%) in gout patients; the following were type 2 diabetes (18.03%) and hyperlipidemia (17.98%). 3. The prevalence of hypertension, hyperlipidemia, type 2 diabetes, chronic heart failure, coronary heart disease, and chronic kidney disease were more prevalent in women (P < 0.05). 4. Gout-hypertension-type 2 diabetes had the highest prevalence in all gout patients. The prevalence of multiple complications showed an increasing trend. 5. Gout- hypertension-type 2 diabetes had the highest prevalence in male and female patients (P < 0.001). Except for the prevalence of gout-hypertension-obesity, gout-obesity-type 2 diabetes and gout-hypertension-obesity-type 2 diabetes, the prevalence of other multiple comorbidities was significantly higher in women (P < 0.001). 6. The average annual cost of hospitalized patients with acute gouty arthritis ranged from RMB 5994.45 to RMB 6709.66, which decreased in women. From 2020 to 2021, the average cost of men with acute gout was much higher than that of women. From 2018 to 2021, the average cost was highest in patients among 40-69 years old.

conclusions1. Gout patients often have single and multiple comorbidities with a higher prevalence in women, and the prevalence showed an increasing trend. 2. Acute gout patients had high hospital costs, and female patients showed a downward trend. Key points • Gout patients have increasing single and multiple comorbidities with a higher prevalence in women. • Acute gout patients had high hospital costs, and female patients showed a downward trend.

Indexed as

Cost of IllnessGoutHospitalizationAdultAgedAged, 80 and overChinaComorbidityDiabetes Mellitus, Type 2FemaleHumansHyperlipidemiasHypertensionMaleMiddle AgedObesityEpidemiologyGoutHospital costMultiple comorbiditiesPrevalence

Identifiers

PMID40954423
PMCPMC12568880

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.