ReviewOdontology2026
Periodontitis and Metabolic Dysfunction-Associated Steatotic Liver Disease: emphasizing the clinical interplay between hepatologists and dentists.
Review in Odontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Metabolomic characteristics and mechanisms of subgingival plaque in MASLD patients with periodontitis.Metabolomics : Official journal of the Metabolomic Society · 2026Article
- Mechanisms underlying the role of the oral-gut-liver axis in the promotion of liver fibrosis by periodontal disease: an interacting network of inflammation, microbiota, and barrier function.Frontiers in cellular and infection microbiology · 2026Review
- Liver Disease and Periodontal Pathogens: A Bidirectional Relationship Between Liver and Oral Microbiota.Dentistry journal · 2025Review
- Oral pathogens meet the gut microbiome: new mechanistic insights on systemic disease.Frontiers in cellular and infection microbiology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This narrative review aims to elucidate the connection between periodontitis and Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), which is currently the most prevalent liver disease. By raising awareness of this link, healthcare providers can enhance their knowledge of the relationship between oral health and liver disease, offering valuable guidance to patients seeking advice from medical and dental professionals. A comprehensive search strategy was implemented to gather relevant literature from various databases, including PubMed, Scopus, and Web of Science. Keywords and controlled vocabulary terms related to MASLD, periodontitis, and their potential connections were used. Emphasis was placed on recent publications to incorporate up-to-date research findings. Various types of studies, such as primary research, systematic reviews, meta-analyses, guidelines, consensus statements, and expert opinions, were considered. The selection of studies focused on understanding the association between MASLD and periodontitis, as well as the underlying mechanisms. Special attention was given to studies exploring the oral-gut-liver axis and the pathogenic links between MASLD and periodontitis. Recent research suggests a possible connection between MASLD and periodontitis, as both conditions share common risk factors such as obesity, insulin resistance, and inflammation. Chronic inflammation associated with periodontitis may contribute to the progression of MASLD by promoting insulin resistance and systemic inflammation. The oral microbiome, which plays a crucial role in periodontitis development, may also influence MASLD pathogenesis. Dysbiosis in the oral microbiome can lead to the translocation of oral bacteria into the bloodstream, triggering systemic inflammation and potentially worsening liver damage in individuals with MASLD. Improving periodontal health can impact the progression of MASLD/MAFLD and enhance patient outcomes. Collaborative care models that integrate dental and medical expertise are crucial for optimal health outcomes in individuals with both conditions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.