Evidence map›Paper›PMID 40954364›Full record

SynthesisJournal of imaging informatics in medicine2026

Accuracy of AI-Based Algorithms in Pulmonary Embolism Detection on Computed Tomographic Pulmonary Angiography: An Updated Systematic Review and Meta-analysis.

Seyed Ali Nabipoorashrafi, Arsalan Seyedi, Razman Arabzadeh Bahri, Amirhossein Yadegar, Mostafa Shomal-Zadeh, Fatemeh Mohammadi, Samira Amin Afshari, Negar Firoozeh, Navida Noroozzadeh, Farbod Khosravi and 2 more

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Journal of imaging informatics in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Seyed Ali NabipoorashrafiCardiothoracic Imaging Section, Department of Radiology, University of Washington, 1959 NE Pacific Street Room RR215F, Box 357115, Seattle, WA, 98195, USA.
Arsalan SeyediEndocrinology and Metabolism Research Center (EMRC), School of Medicine, Vali-Asr Hospital, P.O. Box 13145784, Tehran, Iran.
Razman Arabzadeh BahriUrology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Amirhossein YadegarEndocrinology and Metabolism Research Center (EMRC), School of Medicine, Vali-Asr Hospital, P.O. Box 13145784, Tehran, Iran.
Mostafa Shomal-ZadehEndocrinology and Metabolism Research Center (EMRC), School of Medicine, Vali-Asr Hospital, P.O. Box 13145784, Tehran, Iran.
Fatemeh MohammadiEndocrinology and Metabolism Research Center (EMRC), School of Medicine, Vali-Asr Hospital, P.O. Box 13145784, Tehran, Iran.
Samira Amin AfshariEndocrinology and Metabolism Research Center (EMRC), School of Medicine, Vali-Asr Hospital, P.O. Box 13145784, Tehran, Iran.
Negar FiroozehDepartment of Radiology, University of Washington School of Medicine, Seattle, WA, USA.
Navida NoroozzadehSchool of Medicine, Alborz University of Medical Sciences, Karaj, Alborz, Iran.
Farbod KhosraviCardiothoracic Imaging Section, Department of Radiology, University of Washington, 1959 NE Pacific Street Room RR215F, Box 357115, Seattle, WA, 98195, USA.
Sanaz AsadianCardiothoracic Imaging Section, Department of Radiology, University of Washington, 1959 NE Pacific Street Room RR215F, Box 357115, Seattle, WA, 98195, USA.
Hamid ChalianCardiothoracic Imaging Section, Department of Radiology, University of Washington, 1959 NE Pacific Street Room RR215F, Box 357115, Seattle, WA, 98195, USA. hchalian@uw.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several artificial intelligence (AI) algorithms have been designed for detection of pulmonary embolism (PE) using computed tomographic pulmonary angiography (CTPA). Due to the rapid development of this field and the lack of an updated meta-analysis, we aimed to systematically review the available literature about the accuracy of AI-based algorithms to diagnose PE via CTPA. We searched EMBASE, PubMed, Web of Science, and Cochrane for studies assessing the accuracy of AI-based algorithms. Studies that reported sensitivity and specificity were included. The R software was used for univariate meta-analysis and drawing summary receiver operating characteristic (sROC) curves based on bivariate analysis. To explore the source of heterogeneity, sub-group analysis was performed (PROSPERO: CRD42024543107). A total of 1722 articles were found, and after removing duplicated records, 1185 were screened. Twenty studies with 26 AI models/population met inclusion criteria, encompassing 11,950 participants. Univariate meta-analysis showed a pooled sensitivity of 91.5% (95% CI 85.5-95.2) and specificity of 84.3 (95% CI 74.9-90.6) for PE detection. Additionally, in the bivariate sROC, the pooled area under the curved (AUC) was 0.923 out of 1, indicating a very high accuracy of AI algorithms in the detection of PE. Also, subgroup meta-analysis showed geographical area as a potential source of heterogeneity where the I

Indexed as

AlgorithmsArtificial IntelligenceComputed Tomography AngiographyPulmonary EmbolismHumansSensitivity and SpecificityArtificial intelligencePulmonary embolismTomographyX-ray computed

Identifiers

PMID40954364
PMCPMC13230453

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.