Evidence map›Paper›PMID 40954342›Full record

ArticleJournal of molecular neuroscience : MN2025

Serum Metabolomic Profiling in Possible Early-Stage Multiple Sclerosis: A Targeted

Pınar Şengül, Ahmet Tarık Baykal, Mustafa Serteser

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of molecular neuroscience : MN, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Pınar ŞengülDepartment of Neuroscience, Health Sciences Institute, Acıbadem Mehmet Ali Aydınlar University, Istanbul, Türkiye. neuroscientistpinar@gmail.com.ORCID http://orcid.org/0000-0003-4181-5129
Ahmet Tarık BaykalFaculty of Medicine, Department of Medical Biochemistry, Acıbadem Mehmet Ali Aydınlar University, Istanbul, Istanbul, 34638, Türkiye.ORCID http://orcid.org/0000-0002-8814-7351
Mustafa SerteserFaculty of Medicine, Department of Medical Biochemistry, Acıbadem Mehmet Ali Aydınlar University, Istanbul, Istanbul, 34638, Türkiye.ORCID http://orcid.org/0000-0001-7868-7613

Funding

Acıbadem Mehmet Ali Aydınlar University - Scientific Research Projects Coordination Unit (ACU-BAP) 126
6 · The paper itself

Abstract

Oligoclonal band (OCB) analysis in cerebrospinal fluid (CSF) remains a cornerstone for the early diagnosis of multiple sclerosis (MS), with recent criteria highlighting the κ-free light chain (κ-FLC) index as a sensitive marker of intrathecal immunoglobulin synthesis. However, both approaches rely on lumbar puncture. To address the need for less invasive tools, this study employed proton nuclear magnetic resonance (

Indexed as

MetabolomeMultiple SclerosisOligoclonal BandsAdultBiomarkersFemaleHumansMaleMetabolomicsMiddle AgedProton Magnetic Resonance SpectroscopyBiomarkersOligoclonal Bands1H-NMR spectroscopyAge-adjusted analysisBiomarker discoveryEarly diagnosisKappa indexMultiple sclerosisOligoclonal bandsSerum metabolomics

Identifiers

PMID40954342

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.