Evidence map›Paper›PMID 40954297›Full record

ReviewNature methods2025

MIFA: Metadata, Incentives, Formats and Accessibility guidelines to improve the reuse of AI datasets for bioimage analysis.

Teresa Zulueta-Coarasa, Florian Jug, Aastha Mathur, Josh Moore, Arrate Muñoz-Barrutia, Liviu Anita, Kolawole Babalola, Peter Bankhead, Perrine Gilloteaux, Nodar Gogoberidze and 18 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature methods, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Following a cell's every move.Nature methods · 2025
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Teresa Zulueta-CoarasaEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, UK.ORCID http://orcid.org/0000-0002-0456-6912
Florian JugFondazione Human Technopole, V.le Rita Levi-Montalcini, Milan, Italy.ORCID http://orcid.org/0000-0002-8499-5812
Aastha MathurEuro-BioImaging ERIC Bio-Hub, European Molecular Biology Laboratory (EMBL) Heidelberg, Heidelberg, Germany.
Josh MooreGerman BioImaging - Gesellschaft für Mikroskopie und Bildanalyse e.V., Konstanz, Germany.ORCID http://orcid.org/0000-0003-4028-811X
Arrate Muñoz-BarrutiaUniversidad Carlos III de Madrid, Madrid, Spain.ORCID http://orcid.org/0000-0002-1573-1661
Liviu AnitaEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, UK.
Kolawole BabalolaEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, UK.ORCID http://orcid.org/0000-0003-1384-8433
Peter BankheadEdinburgh Pathology, Centre for Genomic and Experimental Medicine, and CRUK Scotland Centre, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.ORCID http://orcid.org/0000-0003-4851-8813
Perrine GilloteauxNantes Université, CHU Nantes, CNRS, Inserm, BioCore, US16, SFR Bonamy, Nantes, France.ORCID http://orcid.org/0000-0002-4822-165X
Nodar GogoberidzeImaging Platform, Broad Institute, Cambridge, MA, USA.ORCID http://orcid.org/0000-0002-9395-4676
Martin L JonesElectron Microscopy Science Technology Platform, Francis Crick Institute, London, UK.ORCID http://orcid.org/0000-0003-0994-5652
Gerard J KleywegtEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, UK.ORCID http://orcid.org/0000-0002-4670-0331
Paul KorirEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, UK.
Anna KreshukCell Biology and Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany.ORCID http://orcid.org/0000-0003-1334-6388
Aybüke Küpcü YoldaşEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, UK.
Luca MarconatoEuropean Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany.
Kedar NarayanCenter for Molecular Microscopy, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA.ORCID http://orcid.org/0000-0001-7982-6494
Nils NorlinDepartment of Experimental Medical Science, Lund University Bioimaging Centre (LBIC), & Nanolund, Lund University, Lund, Sweden.ORCID http://orcid.org/0000-0003-1970-3198
Bugra OezdemirEuro-BioImaging ERIC Bio-Hub, European Molecular Biology Laboratory (EMBL) Heidelberg, Heidelberg, Germany.ORCID http://orcid.org/0000-0001-9823-0581
Jessica L RiestererCancer Early Detection Advanced Research (CEDAR), Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.ORCID http://orcid.org/0000-0003-1084-2773
Craig RussellEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, UK.
Norman RzepkaScalable Minds GmbH, Potsdam, Germany.ORCID http://orcid.org/0000-0002-8168-7929
Ugis SarkansEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, UK.ORCID http://orcid.org/0000-0001-9227-8488
Beatriz Serrano-SolanoEuro-BioImaging ERIC Bio-Hub, European Molecular Biology Laboratory (EMBL) Heidelberg, Heidelberg, Germany.ORCID http://orcid.org/0000-0002-5862-6132
Christian TischerEuropean Molecular Biology Laboratory, Data Science, Heidelberg, Germany.ORCID http://orcid.org/0000-0003-4105-1990
Virginie UhlmannEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, UK.ORCID http://orcid.org/0000-0002-2859-9241
Vladimír UlmanIT4Innovations, VSB - Technical University of Ostrava, Ostrava-Poruba, Czech Republic.ORCID http://orcid.org/0000-0002-4270-7982
Matthew HartleyEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, UK. matthewh@ebi.ac.uk.ORCID http://orcid.org/0000-0001-6178-2884

Funding

WORK ORDER 126643 B539 EXPAND IC SUITE75N91019D00024 · NIAID · LEIDOS BIOMEDICAL RESEARCH, INC. · PI BRISCOE, LYNN · 2019 to 2025
$3932.6M
NCI NIH HHS 75N91019D00024RCUK | Medical Research Council (MRC) CC1076Wellcome Trust (Wellcome) CC1076
6 · The paper itself

Abstract

Artificial intelligence (AI) methods are powerful tools for biological image analysis and processing. High-quality annotated images are key to training and developing new algorithms, but access to such data is often hindered by the lack of standards for sharing datasets. We discuss the barriers to sharing annotated image datasets and suggest specific guidelines to improve the reuse of bioimages and annotations for AI applications. These include standards on data formats, metadata, data presentation and sharing, and incentives to generate new datasets. We are sure that the Metadata, Incentives, Formats and Accessibility (MIFA) recommendations will accelerate the development of AI tools for bioimage analysis by facilitating access to high-quality training and benchmarking data.

Indexed as

Artificial IntelligenceImage Processing, Computer-AssistedMetadataAlgorithmsGuidelines as TopicHumansInformation Dissemination

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.