ArticleNature immunology2025
Lymph nodes fuel KLF2-dependent effector CD8
Abstract read
In one paragraph
Article in Nature immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- DUSP4 promotes anti-tumor CD8Nature communications · 2026Article
- Spatial Immune Coding in Tumor-Draining Lymph Nodes: Functional Compartmentalization of Immune Activation and Immunosuppression.International journal of molecular sciences · 2026Review
- T-cell miR-155 regulates the response to tumor-specific mRNA vaccines in a murine model of acute myeloid leukemia.Journal of immunology (Baltimore, Md. : 1950) · 2026Article
- New insights into progenitor exhausted T cell populations.Nature reviews. Immunology · 2026Article
- Krüppel-like factors 2 and 3 regulate T cell exhaustion by directing T cell residency and migration.Immunity · 2026Article
- Lymphatic egress recycles tumor-experienced effector CD8 T cells to sustain immune surveillance.bioRxiv : the preprint server for biology · 2026Article
- Aging-Related Morphological Change in Regional Lymph Nodes Promote an Immunosuppressive Microenvironment in Colorectal Cancer.Acta histochemica et cytochemica · 2026Article
- Functions and features of circulating memory T cells.Immunity · 2026Review
- ZFP148 is a transcriptional repressor of cytolytic effector CD8Nature immunology · 2026Article
- Maternal Krüppel-like factor 2 (KLF2)+ CD4 T cells promote fertility and fetal tolerance.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- KLF2 overrides the resident memory CD8 T cell differentiation program, in opposition to KLF3.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- T-cell Priming by High-Avidity Neoantigens in Lymph Nodes Augments Adoptive Immunotherapy.Cancer immunology research · 2026Article
- BACH2 dosage establishes the hierarchy of stemness and fine-tunes antitumor immunity in CAR T cells.Nature immunology · 2026Article
- Tissue-distinct Features of Follicular Cytotoxic CD8bioRxiv : the preprint server for biology · 2026Article
- AblatingFrontiers in immunology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
28 authors.
Carlson Tsui *Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia. carlson.tsui@unimelb.edu.au.ORCID http://orcid.org/0000-0003-0642-814X
Leonie Heyden *Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.ORCID http://orcid.org/0009-0001-2018-8747
Lifen WenDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0003-0229-7306
Catarina Gago da GraçaDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.
Nikita PotemkinDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.
Aleksej FrolovDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0002-4406-1206
Daniel RawlinsonDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0002-3122-6243
Lei QinDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.ORCID http://orcid.org/0009-0004-0572-0338
Verena C WimmerThe Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.
Marjan Hadian-JaziThe Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0002-1948-7491
Darya MalkoDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0002-1262-8378
Chun-Hsi SuDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.
Sining LiDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.ORCID http://orcid.org/0009-0001-4847-7153
Kayla R WilsonDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0003-2023-7964
Helena HorvaticDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0002-4188-4039
Sharanya K WijesingheDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.
Marcela L MoreiraDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0003-3477-0727
Lachlan DryburghDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.ORCID http://orcid.org/0009-0007-5579-7466
Dominik SchienstockDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0001-8440-0009
Lisa RauschDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.
Daniel T UtzschneiderDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0003-2205-9057
Cornelia HalinInstitute of Pharmaceutical Sciences, ETH Zürich, Zürich, Switzerland.ORCID http://orcid.org/0000-0002-7899-2850
Scott N MuellerDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0002-3838-3989
Marc D BeyerImmunogenomics & Neurodegeneration, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.ORCID http://orcid.org/0000-0001-9704-148X
Sammy BedouiDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0002-7443-0543
Zeinab AbdullahInstitute of Molecular Medicine & Experimental Immunology, University Hospital Bonn, Bonn, Germany.
Jan SchröderDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.
Axel KalliesDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia. axel.kallies@unimelb.edu.au.ORCID http://orcid.org/0000-0002-6312-6968
Funding
No grant is acknowledged in the PubMed record.
Abstract
Exhausted CD8
Indexed as
CD8-Positive T-LymphocytesImmune Checkpoint InhibitorsKruppel-Like Transcription FactorsLymph NodesPersistent InfectionAnimalsCell DifferentiationCX3C Chemokine Receptor 1Dendritic CellsLymphocyte ActivationLymphocytic ChoriomeningitisLymphocytic choriomeningitis virusMiceMice, Inbred C57BLMice, KnockoutMice, TransgenicCX3C Chemokine Receptor 1Cx3cr1 protein, mouseImmune Checkpoint InhibitorsKlf2 protein, mouseKruppel-Like Transcription Factors
Identifiers
PMID
40954251What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.