Evidence map›Paper›PMID 40954140›Full record

ReviewACS chemical neuroscience2025

Cell-Penetrating Peptoids: A Dual Functional Strategy for Upcoming Neuroregeneration Application.

Pratikshya Paudel, Rupali Kaur, Prabir Kumar Gharai

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in ACS chemical neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Pratikshya PaudelDepartment of Chemistry, Oklahoma State University, Stillwater, Oklahoma 74078, United States.ORCID 0000-0002-2019-3247
Rupali KaurDepartment of Chemistry, Oklahoma State University, Stillwater, Oklahoma 74078, United States.
Prabir Kumar GharaiDepartment of Animal and Food Sciences, Oklahoma State University, Stillwater, Oklahoma 74078, United States.ORCID 0000-0002-1383-9521

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Effective therapies for neurological conditions are a significant challenge since limited capacity of neurons for regeneration affects neuronal recovery. Despite their ineffective in vivo direct development into neurons, human mesenchymal stem cells (hMSCs) exhibit therapeutic promise through immunological regulation, neuroprotection, and improvement of endogenous repair. A promising strategy is to convert hMSCs into functional neurons using peptoids that also possess cell-penetrating abilities. Therefore, developing cell-penetrating peptoids that combine effective cellular uptake with neural differentiation induction could significantly progress neuroscience research and neuroregenerative treatments.

Indexed as

Cell-Penetrating PeptidesMesenchymal Stem CellsNerve RegenerationPeptoidsAnimalsCell DifferentiationHumansMesenchymal Stem Cell TransplantationNeuronsCell-Penetrating PeptidesPeptoidsCell-penetrating peptoidsHuman mesenchymal stem cellsNeurogenesis

Identifiers

PMID40954140
PMCPMC12498418

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.