Evidence map›Paper›PMID 40953884›Full record

ArticleBMJ open2025

Molecular epidemiology of traumatic brain injury outcome amongst individuals of Black racial identity or African ancestry: a scoping review protocol.

Tadeusz Hayduk Wroblewski, Erum Ajmal, Marie-Claire Roberts, Tim B Bigdeli, Ernest J Barthélemy

Abstract read
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tadeusz Hayduk WroblewskiGlobal Neurosurgery Laboratory, SUNY Downstate Health Sciences University, Brooklyn, New York, USA.ORCID http://orcid.org/0000-0002-8082-1997
Erum AjmalGlobal Neurosurgery Laboratory, SUNY Downstate Health Sciences University, Brooklyn, New York, USA.
Marie-Claire RobertsCollege of Nursing, SUNY Downstate Health Sciences University, Brooklyn, New York, USA.
Tim B BigdeliInstitute for Genomics in Health, SUNY Downstate Health Sciences University, Brooklyn, New York, USA.
Ernest J BarthélemyGlobal Neurosurgery Laboratory, SUNY Downstate Health Sciences University, Brooklyn, New York, USA ernest.barthelemy@downstate.edu.

Funding

Clinical Research Scholars Training (CREST) ProgramR25MD017950 · NIMHD · SUNY DOWNSTATE MEDICAL CENTER · PI Carla Boutin-Foster, Marlene Camacho · 2022 to 2026
$2.6M
NIMHD NIH HHS R25 MD017950
6 · The paper itself

Abstract

introductionTraumatic brain injury (TBI) is a leading cause of mortality and disability worldwide. In the USA, individuals who racially identify as African American or Black experience disproportionately higher rates of TBI and sustain worse prognosis compared with White patients; however, this population continues to be under-represented in contemporary translational research agendas. This protocol aims to comprehensively evaluate and synthesise what is currently known about the molecular epidemiology of TBI outcome among individuals of Black racial identity or African ancestry. METHODS AND ANALYSIS: This review will use the established scoping review framework from the Joanna Briggs Institute. The search strategy will be implemented in PubMed (MEDLINE) and expanded to Embase and Cochrane CENTRAL Library (Wiley) databases in the final review. The date range will span from database inception to 20 July 2025 (date of final search). A two-stage screening process will be performed first at the title and abstract level before full-text assessment. Screening will be performed by two independent reviewers and discrepancies will be reconciled by a third reviewer. Articles that meet the following inclusion criteria will be considered: we will include human studies that investigate molecular and biochemical markers associated with TBI outcome. Studies must include individuals who are (A) of Black or African American racial identity, (B) of African ancestry and/or (C) performed in Sub-Saharan African countries. There is no eligibility criteria related to participant age, sex or gender. Eligible studies will be limited to English, Spanish or French. Data extracted from will be analysed and presented as written narrative, summary statistics of study characteristics and graphical or tabular displays. ETHICS AND DISSEMINATION: Ethical approval is not required for this scoping review. The results of this review will be disseminated through peer-reviewed publications and academic conferences.

Indexed as

Black or African AmericanBlack PeopleBrain Injuries, TraumaticHumansMolecular EpidemiologyResearch DesignScoping Reviews as TopicBrain InjuriesEPIDEMIOLOGYNEUROSURGERY

Identifiers

PMID40953884
PMCPMC12434789

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.