Evidence map›Paper›PMID 40953790›Full record

ArticleThe Annals of thoracic surgery2026

Improving Risk Adjustment in the Assessment of Congenital Heart Center Surgical Quality.

Sharon-Lise Normand, Katya Zelevinsky, Larry Han, Meena Nathan, Haley Abing, John Mayer, Sara K Pasquali

Abstract readMulticenter Study
In one paragraph

Article in The Annals of thoracic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Sharon-Lise NormandDepartment of Health Care Policy, Harvard Medical School, Boston, Massachusetts; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts. Electronic address: sharon@hcp.med.harvard.edu.
Katya ZelevinskyDepartment of Health Care Policy, Harvard Medical School, Boston, Massachusetts.
Larry HanDepartment of Public Health and Health Sciences, Northeastern University, Boston, Massachusetts.
Meena NathanDepartment of Cardiac Surgery, Boston Children's Hospital, Boston, Massachusetts; Department of Surgery, Harvard Medical School, Boston, Massachusetts.
Haley AbingDepartment of Health Care Policy, Harvard Medical School, Boston, Massachusetts.
John MayerDepartment of Cardiac Surgery, Boston Children's Hospital, Boston, Massachusetts; Department of Surgery, Harvard Medical School, Boston, Massachusetts.
Sara K PasqualiDepartment of Pediatrics, University of Michigan C.S. Mott Children's Hospital, Ann Arbor, Michigan.

Funding

Modern Analytics to Improve Quality & Outcome Assessments Following Congenital Heart SurgeryR01HL162893 · NHLBI · HARVARD MEDICAL SCHOOL · PI NORMAND, SHARON-LISE TERESA, PASQUALI, SARA · 2022 to 2025
$2.8M
NHLBI NIH HHS R01 HL162893
6 · The paper itself

Abstract

backgroundUnderstanding center performance in congenital heart surgery remains challenging, with limitations to standard regression approaches. Modern causal inference methods may improve estimation of expected mortality through better balancing case mix but have not been studied.

methodsBenchmark operations across 115 centers (2016-2022) from The Society of Thoracic Surgeons Congenital Database were included. The standard approach uses mixed-effects logistic regression to estimate centers' expected operative mortality inclusive of all patients, even those treated at the center of interest ("target") and those from other centers regardless of how closely aligned with the target they are. The causal approach creates tailored comparison groups, including only similar patients from other centers, by using weights. The study used 3 different weights (entropy balancing weight [EBW], stable balancing weight [SBW], and covariate balancing propensity score [CBPS]) and compared them with standard regression.

resultsAmong 42,579 benchmark operations, overall operative mortality was 2.37%. Centers' mean (25th-75th percentiles [interquartile range; IQR]) regression-based expected mortality was lower (2.03% [IQR, 1.42%-2.58%]) than weighted estimates (EBW, 2.10% [IQR, 1.64%-2.67%]; SBW, 2.09% [IQR, 1.57%-2.69%]; CBPS, 2.10% [IQR, 1.63%-2.66%]) and less variable. The mean ratio of weighted to regression mortality estimate was 1.03 for all estimates, with IQRs: EBW [IQR, 0.89-1.16], SBW [IQR, 0.87-1.15], and CBPS [IQR, 0.92-1.17]. The distributions of operation type and other risk factors were better aligned with the target center in weighted estimates. The largest differences among methods were observed at smaller-volume centers.

conclusionsCausal inference methods constructed more tailored comparison groups for estimating centers' expected mortality, with better alignment of case mix. Adoption of newer approaches may be warranted.

Indexed as

Cardiac Surgical ProceduresHeart Defects, CongenitalQuality ImprovementRisk AdjustmentBenchmarkingFemaleHospital MortalityHumansMaleRetrospective StudiesUnited States

Identifiers

PMID40953790
PMCPMC12513556

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.