Evidence map›Paper›PMID 40953470›Full record

ArticleExperimental physiology2026

NEX4EX - A novel exercise device enabling resistive, plyometric and sensorimotor training during deep-space missions: A case report.

Jonas Böcker, Jochen Zange, Markus Gruber, Guillaume Fau, Rainer Rawer, Sören Törholm, Arnaud Runge, Jörn Rittweger

Abstract readCase Reports
In one paragraph

Article in Experimental physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jonas BöckerInstitute of Aerospace Medicine, German Aerospace Center, Cologne, Germany.ORCID https://orcid.org/0000-0002-2388-0384
Jochen ZangeInstitute of Aerospace Medicine, German Aerospace Center, Cologne, Germany.ORCID https://orcid.org/0000-0003-1822-0952
Markus GruberHuman Performance Research Centre, Department of Sport Science, University of Konstanz, Konstanz, Germany.ORCID https://orcid.org/0000-0002-0233-3912
Guillaume FauSpace Applications Services, Sint-Stevens-Woluwe, Belgium.
Rainer RawerNovotec Medical GmbH, Pforzheim, Germany.
Sören TörholmAnybody Technology, Aalborg, Denmark.
Arnaud RungeEuropean Space Agency ESTEC, Noordwijk, The Netherlands.
Jörn RittwegerInstitute of Aerospace Medicine, German Aerospace Center, Cologne, Germany.

Funding

European Space Agency (ESA) AO/1-9369/18/NL/KML
6 · The paper itself

Abstract

During weightlessness, the human neuro-muscular-skeletal system undergoes maladaptation to the microgravity environment. The European Space Agency (ESA) project NEX4EX, 'Novel Exercise Hardware for Exploration', developed an advanced multipurpose exerciser offering resistive (RES), plyometric (PLYO) and sensorimotor (SENSO) exercises. It is the aim of this case report to assess the functionality of the device. NEX4EX offers RES in terms of squats and heel raises, and PYLO in terms of countermovement jumps and hops. RES and PLYO were compared with standard exercises on ground as reference. SENSO were generated by creating disturbances of the body posture by means of random, rapid pulling on a shoulder harness in four directions and by an oscillating platform. For SENSO, the results showed clear postural reflexes in trunk and leg muscles to stabilise upright posture after perturbation stimuli at the shoulders. RES and PLYO were carried out accurately on NEX4EX by the participants, but with reduced loads compared to reference (up to -37% for RES; up to -24% for PLYO). This resulted in reduced muscle activation for RES, whereas the muscle activation stayed comparable for PLYO. A reduced maximum take-off velocity during PLYO (up to -66%) was shown leading to a reduced jump height (up to -72%). Although some exercises could not be performed with the same intensity with NEX4EX, in general it enabled all intended exercises. The basic functionality of the device was shown, and thus the device showed its potential as an integrative countermeasure device for upcoming deep-space missions.

Indexed as

Plyometric ExerciseResistance TrainingSpace FlightAdultHumansMaleMuscle, SkeletalPostureWeightlessnesscase reportcountermeasure exerciseplyometric trainingresistive trainingsensorimotor training

Identifiers

PMID40953470
PMCPMC13394085

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.