Evidence map›Paper›PMID 40953258›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

LDL receptor promotes urinary tract infection by α-hemolysin-producing

Lena Possenriede, Georg W Sendtner, Peyman Falahat, Julia Miranda, Axel Schmidt, Kerstin U Ludwig, Sibylle von Vietinghoff

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Monocyte Chemokines Enhance Atherosclerotic Plaque Necrosis After Bacterial Kidney Infection.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  2. Reply to Possenriede et al.: LDLR as a targetable HlyA receptor inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lena PossenriedeNephrology Section, Medical Clinic 1, University Hospital Bonn, Rheinische Friedrich-Wilhelms Universität, Bonn D-53127, Germany.
Georg W SendtnerNephrology Section, Medical Clinic 1, University Hospital Bonn, Rheinische Friedrich-Wilhelms Universität, Bonn D-53127, Germany.
Peyman FalahatNephrology Section, Medical Clinic 1, University Hospital Bonn, Rheinische Friedrich-Wilhelms Universität, Bonn D-53127, Germany.
Julia MirandaNephrology Section, Medical Clinic 1, University Hospital Bonn, Rheinische Friedrich-Wilhelms Universität, Bonn D-53127, Germany.
Axel SchmidtInstitute for Human Genetics, University Hospital Bonn, Rheinische Friedrich-Wilhelms Universität, Bonn D-53127, Germany.
Kerstin U LudwigInstitute for Human Genetics, University Hospital Bonn, Rheinische Friedrich-Wilhelms Universität, Bonn D-53127, Germany.
Sibylle von VietinghoffNephrology Section, Medical Clinic 1, University Hospital Bonn, Rheinische Friedrich-Wilhelms Universität, Bonn D-53127, Germany.ORCID 0000-0002-3217-5433

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40953258
PMCPMC12478150

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.