Evidence map›Paper›PMID 40952827›Full record

ReviewAnnals of African medicine2026

Asymptomatic Complete Heart Block in an Adult with Down's Syndrome and Structurally Normal Heart: A Rare Association.

Sangram Mangudkar, Nallani Chakravarthi Sai Sirisha, Vijayashree Gokhale, Divam Prakash Singh

Abstract readCase ReportsReview
In one paragraph

Review in Annals of African medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sangram MangudkarDepartment of General Medicine, Dr. D. Y. Patil Medical College, Hospital and Research Centre, and Dr. D. Y. Patil Vidyapeeth, Pimpri, Pune, Maharashtra, India.
Nallani Chakravarthi Sai Sirisha
Vijayashree Gokhale
Divam Prakash Singh

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

abstractDown's syndrome (DS) is caused by an extra copy of the chromosome 21. Patients with DS have short stature, intellectual impairment, and characteristic physical features. Cardiovascular disease is the leading cause of morbidity and mortality in patients with DS. An estimated 40%-60% of DS patients have congenital heart disease (CHD). Cardiac conduction disturbances in association with CHD have been described in patients with DS. However, isolated cardiac conduction defect is exceptionally rare in DS, and we report an unusual case of asymptomatic complete heart block in an adult case of DS with structurally normal heart and review the literature about the conduction disturbances in DS.

Indexed as

Down SyndromeHeart BlockElectrocardiographyHumansBloc cardiaque completComplete heart blockconduction disturbanceDown’s syndromesyndrome de Downtrouble de la conduction

Identifiers

PMID40952827
PMCPMC13374961

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.