Evidence map›Paper›PMID 40952808›Full record

ArticleJournal of the American Society of Nephrology : JASN2026

Metabolic Dysregulation of 27-Hydroxycholesterol Sensitizes Proximal Tubular Epithelial Cells to Ferroptosis in Ischemic Acute Kidney Injury.

Yi-Lin Zhang, Xin-Yan Li, Tao-Tao Tang, Qin Yang, Bo Wang, Zuo-Lin Li, Yi Wen, Qiu-Li Wu, Lin-Li Lv, Ye Feng and 4 more

Abstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yi-Lin ZhangInstitute of Nephrology, Zhong Da Hospital, Southeast University School of Medicine, Nanjing, China.
Xin-Yan LiInstitute of Nephrology, Zhong Da Hospital, Southeast University School of Medicine, Nanjing, China.ORCID 0009-0000-1877-0554
Tao-Tao TangInstitute of Nephrology, Zhong Da Hospital, Southeast University School of Medicine, Nanjing, China.
Qin YangInstitute of Nephrology, Zhong Da Hospital, Southeast University School of Medicine, Nanjing, China.
Bo WangInstitute of Nephrology, Zhong Da Hospital, Southeast University School of Medicine, Nanjing, China.
Zuo-Lin LiInstitute of Nephrology, Zhong Da Hospital, Southeast University School of Medicine, Nanjing, China.
Yi WenInstitute of Nephrology, Zhong Da Hospital, Southeast University School of Medicine, Nanjing, China.ORCID 0000-0002-7288-3020
Qiu-Li WuInstitute of Nephrology, Zhong Da Hospital, Southeast University School of Medicine, Nanjing, China.ORCID 0000-0002-9488-7989
Lin-Li LvInstitute of Nephrology, Zhong Da Hospital, Southeast University School of Medicine, Nanjing, China.ORCID 0009-0001-3330-1489
Ye FengInstitute of Nephrology, Zhong Da Hospital, Southeast University School of Medicine, Nanjing, China.
Xiong-Zhong RuanKey Laboratory of Molecular Biology on Infectious Diseases, Centre for Lipid Research, Ministry of Education, Chongqing Medical University, Chongqing, China.ORCID 0000-0001-5199-4971
John Ci-Jiang HeDepartment of Medicine, Icahn School of Medicine at Mount Sinai, Division of Nephrology, New York, New York.ORCID 0000-0002-1502-2849
Bin WangInstitute of Nephrology, Zhong Da Hospital, Southeast University School of Medicine, Nanjing, China.ORCID 0000-0003-1606-5004
Bi-Cheng LiuInstitute of Nephrology, Zhong Da Hospital, Southeast University School of Medicine, Nanjing, China.ORCID 0000-0002-6694-8406

Funding

Jiangsu Provincial Key Research and Development Program BE2023770National Key Research and Development Program 2022YFC2502500National Natural Science Foundation of China 82030024National Natural Science Foundation of China 82070735National Natural Science Foundation of China 82230022National Natural Science Foundation of China 82241047National Natural Science Foundation of China 82470770National Outstanding Doctor Program CZXM-GSP-RC161Research Personnel Cultivation Programme of Zhongda Hospital Southeast University CZXM-GSP-RC150Young Scholars of Yangtze River Scholar Professor Program 2023 BW
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AKIcell deathischemia-reperfusionlipidsmetabolismmetabolomics

Identifiers

PMID40952808
PMCPMC12935325

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.