Evidence map›Paper›PMID 40952610›Full record

ArticleCardiovascular intervention and therapeutics2026

Analysis of predictors of paravalvular leakage after transcatheter aortic valve implantation with fifth-generation self-expandable valve.

Motoki Kojima, Shinichiro Fujimoto, Masahiko Noguchi, Yui Okada Nozaki, Hideyuki Sato, Yuko Okano Kawaguchi, Nobuo Tomizawa, Shinichiro Doi, Shinya Okazaki, Kazuhiko Doryo and 3 more

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Article in Cardiovascular intervention and therapeutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Motoki KojimaDepartment of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, 2-1-1 Hongo Bunkyo-Ku, Tokyo, 113-8421, Japan.
Shinichiro FujimotoDepartment of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, 2-1-1 Hongo Bunkyo-Ku, Tokyo, 113-8421, Japan. s-fujimo@tj8.so-net.ne.jp.
Masahiko NoguchiDepartment of Cardiology, Tokyo Bay Urayasu Ichikawa Medical Center, Urayasu, Japan.
Yui Okada NozakiDepartment of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, 2-1-1 Hongo Bunkyo-Ku, Tokyo, 113-8421, Japan.
Hideyuki SatoDepartment of Diagnostic Radiological Technology, Juntendo University Hospital, Tokyo, Japan.
Yuko Okano KawaguchiDepartment of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, 2-1-1 Hongo Bunkyo-Ku, Tokyo, 113-8421, Japan.
Nobuo TomizawaDepartment of Radiology, Juntendo University Hospital, Tokyo, Japan.
Shinichiro DoiDepartment of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, 2-1-1 Hongo Bunkyo-Ku, Tokyo, 113-8421, Japan.
Shinya OkazakiDepartment of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, 2-1-1 Hongo Bunkyo-Ku, Tokyo, 113-8421, Japan.
Kazuhiko DoryoDepartment of Radiological Technology, Juntendo University Nerima Hospital, Tokyo, Japan.
Yosuke KogureDepartment of Diagnostic Radiological Technology, Juntendo University Hospital, Tokyo, Japan.
Minoru TabataDepartment of Cardiovascular Surgery, Juntendo University Hospital, Tokyo, Japan.
Tohru MinaminoDepartment of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, 2-1-1 Hongo Bunkyo-Ku, Tokyo, 113-8421, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paravalvular leakage (PVL) is one of the complications of transcatheter aortic valve implantation (TAVI), and its occurrence has been reported to affect long-term prognosis. We investigated whether the aortic valve calcification measured on preoperative CT is useful in predicting PVL after TAVI using the fifth-generation self-expanding valves. We analyzed 88 consecutive patients who underwent TAVI with the fifth-generation self-expanding valve from March 2023 to March 2024. Significant PVL was defined as PVL of mild or greater based on postoperative echocardiography results. We performed logistic regression analysis to evaluate whether patient background, and aortic valve calcification volume (AVCa-Vol), maximum CT value (AVCa-Max), mean CT value (AVCa-Ave), Agatston score (AV-Aga) and left ventricular outflow tract (LVOT) calcification volume measured by ECG-gated non-contrast CT were significant predictors. Mild or greater PVL was observed in 26 patients (29.5%). AVCa-Vol (1948.9 mm

Indexed as

Aortic ValveAortic Valve StenosisCalcinosisHeart Valve ProsthesisPostoperative ComplicationsTranscatheter Aortic Valve ReplacementAgedAged, 80 and overEchocardiographyFemaleHumansMaleProsthesis DesignRetrospective StudiesRisk FactorsTomography, X-Ray ComputedCalcificationParavalvular leakageSelf-expandableTranscatheter aortic valve implantation

Identifiers

PMID40952610

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.