Evidence map›Paper›PMID 40952606›Full record

ArticleJournal of nephrology2025

A life cycle assessment of peritoneal dialysis procurement in Italy: environmental burden and opportunities for improvement.

James Larkin, Giulia Ligabue, Gaetano Alfano, Rodrigo Martínez Cadenas, Abass Fehintola, Ingeborg Steinbach, Aycan Yasar, Niccolo Morisi, Marta Arias-Guillen, Marialuisa Caiazzo and 2 more

Abstract read
In one paragraph

Article in Journal of nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

James LarkinSchool of Dental, Child and Public Health, Trinity College Dublin, Dublin, Ireland. larkinj4@tcd.ie.ORCID http://orcid.org/0009-0007-5152-2414
Giulia LigabueNephrology Dialysis and Kidney Transplant Unit, Azienda Ospedaliero Universitaria di Modena, Modena, Italy.ORCID http://orcid.org/0000-0002-0043-2300
Gaetano AlfanoNephrology Dialysis and Kidney Transplant Unit, Azienda Ospedaliero Universitaria di Modena, Modena, Italy.ORCID http://orcid.org/0000-0003-0591-8622
Rodrigo Martínez CadenasUniversidad Autonoma de Madrid, Madrid, Spain.ORCID http://orcid.org/0009-0002-9899-739X
Abass FehintolaSchool of Dental, Child and Public Health, Trinity College Dublin, Dublin, Ireland.ORCID http://orcid.org/0009-0000-6299-7932
Ingeborg SteinbachCentre for Sustainable Healthcare, Oxford, UK.ORCID http://orcid.org/0000-0002-6326-9651
Aycan YasarCentre for Sustainable Healthcare, Oxford, UK.
Niccolo MorisiNephrology Dialysis and Kidney Transplant Unit, Azienda Ospedaliero Universitaria di Modena, Modena, Italy.ORCID http://orcid.org/0009-0000-0753-3326
Marta Arias-GuillenCentre for Sustainable Healthcare, Oxford, UK.ORCID http://orcid.org/0000-0001-8023-2589
Marialuisa CaiazzoMozarc Medical, Mirandola, Italy.
Gabriele DonatiNephrology Dialysis and Kidney Transplant Unit, Azienda Ospedaliero Universitaria di Modena, Modena, Italy.ORCID http://orcid.org/0000-0001-8549-1221
Brett DuaneSchool of Dental, Child and Public Health, Trinity College Dublin, Dublin, Ireland.ORCID http://orcid.org/0000-0001-9670-0594

Funding

H2020 Science with and for Society 101137054
6 · The paper itself

Abstract

backgroundProcurement activities in healthcare, especially within nephrology, contribute significantly to the environmental footprint. In peritoneal dialysis (PD), procurement of consumables such as dialysis bags, tubing, and machines plays a critical role in driving environmental impacts. Previous studies, including those by the National Health Service (NHS), have shown that procurement can account for up to 72% of the healthcare sector's carbon emissions.

methodsA life cycle assessment (LCA) was conducted from April to July 2024 at the Nephrology Dialysis and Kidney Transplantation Unit of AOU Policlinico di Modena, Italy, in accordance with ISO 14040/14044 standards. The study focused on procurement-related environmental impacts in automated peritoneal dialysis (APD), based on a standard prescription of two 5L bags overnight and one 2L daytime dwell per day. Products were dismantled to assess materials and modelled using OpenLCA with the Ecoinvent v3.10 database. Transportation, manufacturing, and waste disposal were included within system boundaries.

resultsThe 5L Dialysate Bag (used twice daily) had the highest carbon footprint (1515 kg carbon dioxide equivalent [CO

conclusionThe environmental impact of PD procurement is concentrated in a few high-use, high-impact items. Reduction strategies should target material substitutions, modular product design, and lower-emission transport and energy use. Innovations such as local dialysate mixing, improved waste segregation, and increased recyclability could substantially reduce the environmental burden of PD.

Indexed as

Carbon FootprintPeritoneal DialysisHumansItalyCarbon footprintEnvironmental impactHealthcare wasteLCALife cycle assessmentPeritoneal dialysisPlasticsProcurementPVCSustainability

Identifiers

PMID40952606
PMCPMC12630254

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.