Evidence map›Paper›PMID 40952500›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Three-dimensional quantitative CT analysis of the C2 spinous process and its implications for spinous process screw fixation.

Guanyi Liu, Lushuang Ye, Renhai Feng, Shuping Cai, Changting Wu, Yizhong Ma, Yong Hu, Qing Li, Binqiang Pan

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Guanyi LiuNingbo No.6 hospital, Ningbo, China.
Lushuang YeNingbo No.6 hospital, Ningbo, China.
Renhai FengNingbo No.6 hospital, Ningbo, China.
Shuping CaiNingbo No.6 hospital, Ningbo, China.
Changting WuNingbo No.6 hospital, Ningbo, China.
Yizhong MaNingbo University, Ningbo, China.
Yong HuNingbo No.6 hospital, Ningbo, China.
Qing LiNingbo Yinzhou No.2 Hospital, Ningbo, China. liqing877@126.com.
Binqiang PanNingbo No.6 hospital, Ningbo, China. 1556833295@qq.com.

Funding

Ningbo Clinical Research Center for Orthopedics, Sports Medicine & Rehabilitation. 2024L004
6 · The paper itself

Abstract

objectiveTo perform a three-dimensional quantitative computed tomography (CT) analysis of the C2 spinous process and compare the morphometric feasibility of three spinous process screw fixation techniques-vertical, horizontal, and oblique trajectories-to guide clinical applications when conventional C2 fixation is not feasible.

methodsCT data from 100 adults (aged 20-70 years) without cervical pathology were retrospectively analyzed. Three-dimensional reconstructions of the C2 vertebra were generated using 3D Slicer software. Morphometric parameters of the spinous process-including height and transverse width at the base, midsection, and tip-were measured. Simulated screw trajectories representing vertical, horizontal, and oblique fixation were modeled in AutoCAD and virtually inserted into the 3D reconstructions using 3D Slicer to calculate trajectory lengths. Gender differences and correlations with age were also analyzed.

resultsThe mean spinous process height was 10.50 ± 2.54 mm, decreasing significantly from base to tip (P < 0.001). The width of the spinous process demonstrated a triangular configuration, progressively increasing from cephalic to caudal. Males had significantly greater spinous process widths than females (P < 0.05). Among the three trajectories, horizontal fixation yielded the longest screw path (20.65 ± 3.68 mm), followed by oblique (17.70 ± 3.14 mm) and vertical (14.79 ± 2.19 mm) approaches (P < 0.001). No significant correlations were observed between morphometric parameters and age.

conclusionThe C2 spinous process provides sufficient anatomical space for screw fixation. Horizontal and oblique screw trajectories offer longer and potentially more stable fixation paths and may serve as effective alternatives in salvage or supplementary scenarios.

Indexed as

Bone ScrewsCervical VertebraeImaging, Three-DimensionalSpinal FusionTomography, X-Ray ComputedAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesYoung AdultAnatomyC2FixationSpinous process

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.