Evidence map›Paper›PMID 40952461›Full record

Trial reportOrthopadie (Heidelberg, Germany)2026

Improved accuracy of functional alignment restoration with robotic-assisted total knee arthroplasty : A quasi-randomized controlled trial.

Filippo Migliorini, Luise Schäfer, Jens Schneider, Andrea Maria Nobili, Daniel Kämmer, Andreas Bell

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Orthopadie (Heidelberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Filippo MiglioriniDepartment of Trauma and Reconstructive Surgery, University Hospital Halle, Martin-Luther University Halle-Wittenberg, Ernst-Grube-Street 40, 06097, Halle (Saale), Germany. filippo.migliorini@uk-halle.de.ORCID http://orcid.org/0000-0001-7220-1221
Luise SchäferDepartment of Orthopaedic and Trauma Surgery, Eifelklinik St. Brigida, Kammerbruschstr. 8, 52152, Simmerath, Germany.
Jens SchneiderDepartment of Orthopaedic and Trauma Surgery, Eifelklinik St. Brigida, Kammerbruschstr. 8, 52152, Simmerath, Germany.
Andrea Maria NobiliDepartment of Orthopaedic and Trauma Surgery, Eifelklinik St. Brigida, Kammerbruschstr. 8, 52152, Simmerath, Germany.
Daniel KämmerDepartment of Orthopaedic and Trauma Surgery, Eifelklinik St. Brigida, Kammerbruschstr. 8, 52152, Simmerath, Germany.
Andreas BellDepartment of Orthopaedic and Trauma Surgery, Eifelklinik St. Brigida, Kammerbruschstr. 8, 52152, Simmerath, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesThis quasi-randomized controlled trial compared robotic-assisted and conventional total knee arthroplasty (TKA) in restoring patient-specific coronal alignment according to a functional alignment philosophy. Outcomes included preservation of the anatomical hip-knee-ankle angle (aHKA), mechanical axis deviation (MAD), and component positioning. Subgroup analyses assessed consistency in valgus and varus morphotypes. MATERIAL AND

methodsA single-blind parallel group quasi-RCT was conducted at the Department of Orthopedic Surgery, Eifelklinik St. Brigida, Germany (2021-2025). Patients underwent TKA following identical perioperative pathways. All procedures used a medial parapatellar approach and Smith & Nephew Legion Genesis II implants.

resultsA total of 692 patients were enrolled (346 robotic, 346 freehand). Baseline characteristics were comparable. Postoperative HKA was similar between groups, but the robotic group achieved a significantly smaller aHKA delta (2.58° vs 4.49°, p = 0.002). Robotic-assisted TKA preserved joint line alignment more consistently in valgus (2.63° vs 5.72°, p = 0.03) and varus knees (2.56° vs 4.22°, p = 0.004). The MAD control was improved, while differences n the mechanical lateral distal femoral angle (mLDFA) and mechanical medial proximal tibial angle (mMPTA) were not significant.

conclusionRobotic-assisted TKA enhanced accuracy in reproducing native joint line orientation, offering more consistent preservation of joint line obliquity in both valgus and varus morphotypes, thus supporting its role in personalized alignment strategies.

Indexed as

Arthroplasty, Replacement, KneeBone MalalignmentOsteoarthritis, KneeRobotic Surgical ProceduresAgedFemaleHumansKnee JointKnee ProsthesisMaleMiddle AgedSingle-Blind MethodTreatment OutcomeCoronal planeJoint line obliquityRobotic surgeryValgus kneeVarus deformity

Identifiers

PMID40952461
PMCPMC12881118

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.