Observational studyIndian journal of pediatrics2025
Clinico-Epidemiological Profile of Intussusception Among Children Younger than 2 Years in Karnataka, India: A Multicenter Hospital-based Surveillance Study.
Observational study in Indian journal of pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors.
Funding
Abstract
objectivesImmunization with conventional rotavirus vaccines (RVVs) has been reported to intensify the risk of intussusception (IS). However, the risk of IS following vaccination with the recently introduced ROTASIIL is not clearly understood. The aim of this study was to describe the clinical and epidemiological profile of IS among children after vaccination with RVV.
methodsA hospital-based multicenter observational study was carried out at five private medical college-based tertiary care hospitals in Karnataka, India, over a 30-mo period. Children younger than 2 y admitted with confirmed IS were enrolled. Data were collected on demographics, clinical features, and vaccination history.
resultsOf 196 children with confirmed IS, 153 (78%) had received ROTASIIL. The median age (interquartile range [IQR]) of the participants was 9 (6–14) mo, and 69% were male. The median age (IQR) at receiving first, second, and third dose of RVV was 7 (6–9) wk, 12 (11–14) wk, and 17 (16–20) wk, respectively. Of the participants, 91.8% had ileo-colic IS and the IS was resolved by imaging-guided reduction in 78.6%. Two, three, and eleven cases of IS were reported within 21 d after receiving the first, second and third dose of RVV, respectively.
conclusionsThis study provides baseline epidemiological data on IS among children younger than 2 y. Although, no definite association between ROTASIIL and IS was noted, this study provides health authorities with information on the risks and benefits of ROTASIIL in a real-world setting.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.