Evidence map›Paper›PMID 40952297›Full record

ArticleAsian Pacific journal of cancer prevention : APJCP2025

Green Synthesis of Silver Nanoparticles Using the Seeds of Lupinus luteus: Characterization and Assessment the Antibacterial and Anticancer Activities.

Noor H Faisal, Nuha A M Obaid, Nuha W Ali, Ali A A Al-Shawi, Ruaa G Ibrahim, Ayat N Hassan, Ayat J Kadhum, Osama A Mohsein, Iman N Luaibi

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Article in Asian Pacific journal of cancer prevention : APJCP, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Noor H FaisalDepartment of Chemistry, College of Education for Pure Sciences, University of Basrah, Basrah, Iraq.ORCID 0009-0008-7027-1187
Nuha A M ObaidDepartment of Chemistry, College of Education for Pure Sciences, University of Basrah, Basrah, Iraq.
Nuha W AliDepartment of Chemistry, College of Education for Pure Sciences, University of Basrah, Basrah, Iraq.
Ali A A Al-ShawiDepartment of Chemistry, College of Education for Pure Sciences, University of Basrah, Basrah, Iraq.ORCID 0000-0002-0690-4612
Ruaa G IbrahimDepartment of Chemistry, College of Education for Pure Sciences, University of Basrah, Basrah, Iraq.
Ayat N HassanDepartment of Chemistry, College of Education for Pure Sciences, University of Basrah, Basrah, Iraq.
Ayat J KadhumDepartment of Chemistry, College of Education for Pure Sciences, University of Basrah, Basrah, Iraq.
Osama A MohseinDepartment of Medical Laboratory Techniques, Mazaya University College, Thi-Qar, Iraq.ORCID 0009-0004-5628-2328
Iman N LuaibiDepartment of Basic Sciences, College of Dentistry, University of Basrah, Basrah, Iraq.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to synthesize silver nanoparticles using the aqueous seed extract of Lupinus luteus via a green synthesis approach, and to evaluate their antibacterial and anticancer activities against liver and breast cancer cell lines. MATERIALS AND

methodssilver nanoparticles (AgNPs) were synthesized using essential extracts from Lupinus luteus. The AgNPs were subsequently characterized using ultraviolet - visible spectroscopy, scanning electron microscopy, and Fourier transform infrared spectroscopy. The biological activities of AgNPs were examined.  Results: The present study indicates that silver nanoparticles produced of Lupinus luteus extracts show an absorption peak at 420 nm, thereby confirming their successful synthesis. A study using scanning electron microscopy (SEM) showed that the nanoparticles' average diameter is 24.72 nm. The biological activities of these nanoparticles were examined, including their antibacterial and anticancer capabilities. Assays include flow cytometry, half-maximal inhibitory concentration (IC50), and minimum inhibitory concentration (MIC) were used in the biological activity evaluation. The nanoparticles caused cell cycle arrest at the S-phase in two human cancer cell lines, HepG2 and MCF-7.

conclusionThese results demonstrate how Lupinus luteus nanoparticles may be used to create cutting-edge antibacterial and anticancer treatments. Therefore, merit investigation request to develop it functions.

Indexed as

Anti-Bacterial AgentsAntineoplastic AgentsGreen Chemistry TechnologyLupinusMetal NanoparticlesPlant ExtractsSeedsSilverApoptosisBreast NeoplasmsCell ProliferationHumansMCF-7 CellsMicrobial Sensitivity TestsAnti-Bacterial AgentsAntineoplastic AgentsPlant ExtractsSilverantibacterialAnticancerLupinus luteusSilver nanoparticles

Identifiers

PMID40952297
PMCPMC12882025

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.