ArticleAsian Pacific journal of cancer prevention : APJCP2025
The Effect of Resistance Training on Serum Levels of Lipid Profile and Liver Enzymes in Male Rat Undergoing Radiotherapy.
Article in Asian Pacific journal of cancer prevention : APJCP, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundThis study investigated the effects of resistance training on lipid profiles and liver enzyme levels in male rats exposed to x-ray radiation.
methodsIn this experimental study, 24 eight-week-old Sprague Dawley rats (200-250g) were randomly assigned into four groups: healthy control, irradiated control, healthy resistance training, and irradiated resistance training. Irradiation was induced at a dose of 4 Gy on the whole body. The resistance training protocol was performed for ten weeks. Finally, blood serum was used to assess AST, ALT, ALP and testosterone, and lipid profile. Data were analyzed using ANOVA and Tukey's post hoc test using SPSS-16 software at a 0.05 level of significance.
resultsThe results showed that radiation significantly increased serum levels of AST (169.3±2.4 vs 131.1±2.4, P=0.001), ALT (75.6±3.6 vs 65.1±3.1, P=0.002), and ALP (503.5±83.1 vs 370.3±66.9, P=0.034) between radiation control and healthy control groups. Also, no significant difference was observed between serum levels of AST (P=1.000) ALT (P=0.942), and ALP (P=0.925) in radiation resistance training and the healthy control groups. In addition, a significant increase was observed between radiation control and radiation resistance training groups in lipid profiles (P≥0.05). Also, no significant difference was observed between serum levels of TG (P=0.212) LDL-C (P=0.931), and HDL-C (P=0.992) in radiation resistance training and the healthy control groups.
conclusionsOur findings suggest that resistance training may improve lipid profiles and liver enzyme levels in male rats exposed to x-ray radiation.
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