SynthesisAsian Pacific journal of cancer prevention : APJCP2025
Exposing the Influence of Preceding Sexual Behavior in Younger Years toward Prostate Cancer Occurrence: Qualitative Mapping on Sexual Risk Factors.
Synthesis in Asian Pacific journal of cancer prevention : APJCP, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Exposing the Influence of Preceding Sexual Behavior in Younger Years toward Prostate Cancer Occurrence: Qualitative Mapping on Sexual Risk Factors.Asian Pacific journal of cancer prevention : APJCP · 2025Pooled it
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionProstate cancer (PCa) is a multifactorial disease influenced by genetic, hormonal, and lifestyle factors, yet the impact of preceding sexual behaviors remains underexplored. Given the prostate's fundamental role in male sexual function, this study aims to qualitatively assess the relationship between ejaculation frequency (EF), first sexual activity (FSA), and lifetime sexual partner (SP) count with PCa occurrence in later life. MATERIALS &
methodsA systematic literature review was conducted following PRISMA guidelines, with studies identified through MEDLINE, ScienceDirect, and ProQuest databases. Retrospective cohort and case-control studies published since 2000, examining PCa risk in relation to sexual behaviors in early adulthood (20s-40s), were included. Data extraction focused on EF, FSA, and SP count, and study quality was assessed using the Newcastle-Ottawa Scale.
resultsA total of 10 studies with 6,601 PCa cases and 6,208 controls were analyzed. Higher EF from sexual intercourse (SI; ≥5-12 times per month) was associated with a reduced PCa risk, whereas frequent masturbation (≥2-7 times per week) showed a potential risk increase. The influence of FSA was inconsistent, with some studies linking earlier or later initiation to higher risk. A higher lifetime SP count (7-21 partners) was generally associated with increased PCa risk, likely due to sexually transmitted infections and chronic inflammation.
conclusionSexual behaviors in younger years may play a role in PCa development, with EF type, FSA, and SP count acting as potential risk modifiers. While high EF from SI may be protective, excessive masturbation and multiple partners could contribute to risk. Further prospective studies are needed to refine recommendations on sexual health and prostate cancer prevention.
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