ReviewAsian Pacific journal of cancer prevention : APJCP2025
The Role of lncRNAs in the Epithelial-Mesenchymal Transition in Cervical Cancer: A Narrative Review.
Review in Asian Pacific journal of cancer prevention : APJCP, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Long non-coding RNA POC1B-AS1 depletion represses colorectal cancer progression through the microRNA-625-5p/FOXK1 axis.American journal of translational research · 2025Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveIn this context, the aim of this study was to compile the main works that address the relationship between lncRNAs and Epithelial-Mesenchymal Transition (EMT) in cervical cancer.
methodsData extraction was conducted using the PubMed database, where a search for selected studies on lncRNAs involved in EMT in cervical cancer was performed. The search was based on the following keywords: "Epithelial-Mesenchymal Transition" AND "Uterine Cervical Neoplasms" and "lncRNA and EMT and cervical cancer."
resultIncluded in this study were 16 lncRNAs, which encompass expression level, microRNAs, targets, clinical significance, and references. Among the 16 lncRNAs observed, it was found that 5 of them can regulate EMT by modulating microRNAs. It was also noted that these biomolecules are capable of regulating the expression of important EMT genes, such as SNAIL, SLUG, and TWIST, thus influencing cancer invasion and metastasis. In addition to these, 11 lncRNAs were found, which can regulate biological pathways such as Wnt/β-catenin and AKT/mTOR, playing fundamental roles in EMT. In conclusion, the future prospects of lncRNAs in therapy and inhibition of EMT are promising.
conclusionConsidering the relevance of EMT to cancer progression and the involvement of lncRNAs in this biological process, it becomes important to better understand their role and the possibility of targeting them therapeutically, which can represent significant advancements in the treatment not only of cancer but also of other diseases.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.