Evidence map›Paper›PMID 40952102›Full record

ArticlemSystems2025

Multi-omics analysis reveals important role for microbial-derived metabolites from

Dulce G Guillén Matus, Caroline M Donaghy, Nidhi Vijayan, Zachary T Lane, Matthew Howell, George G Glavin, Alfredo M Angeles-Boza, Spencer V Nyholm, Marcy J Balunas

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mSystems, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dulce G Guillén Matus *Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0002-3627-6186
Caroline M Donaghy *Department of Chemistry, University of Connecticut, Storrs, Connecticut, USA.ORCID 0000-0002-9746-9440
Nidhi Vijayan *Department of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut, USA.ORCID 0000-0002-0615-9587
Zachary T LaneDepartment of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut, USA.ORCID 0000-0003-2577-4929
Matthew HowellDepartment of Chemistry, University of Connecticut, Storrs, Connecticut, USA.
George G GlavinSaint-Gobain Research North America, Northborough, Massachusetts, USA.
Alfredo M Angeles-BozaDepartment of Chemistry, University of Connecticut, Storrs, Connecticut, USA.ORCID 0000-0002-5560-4405
Spencer V NyholmDepartment of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut, USA.ORCID 0000-0001-5597-1945
Marcy J BalunasDepartment of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0003-2374-4048

Funding

NSF | National Science Foundation Graduate Research Fellowship Program (GRFP) DGE-1747453University of Connecticut Convergence Awards for Research in Interdisciplinary Centers (CARIC)
6 · The paper itself

Abstract

Marine microbial communities govern many of the biological and chemical processes in the ocean, including element cycles, ecosystem health, and disease. Marine organisms are surrounded by microbes, with complex molecular interactions occurring between bacterial symbionts, eukaryotic hosts, and their pathogens or prey. Trace metals in the ocean can be either beneficial or detrimental to marine life depending on their concentrations and bioavailability. Multiple marine tunicate species are known to bioaccumulate trace metals in their mantel, and research suggests that tunicate microbiota plays an important role in this process.

Indexed as

BacteriaMetabolomeMetalsMicrobiotaUrochordataAnimalsMetabolomicsMultiomicsMetalsBotryllus schlosserihost-microbe-metal interactionsmarine tunicatesmetabolome and pan-metabolomemetallomemicrobiomemulti-omics data integration

Identifiers

PMID40952102
PMCPMC12542763

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.