Evidence map›Paper›PMID 40951857›Full record

ArticleJournal of mid-life health

Primary Squamous Cell Carcinoma of Breast: A Short Report and Immunohistochemical Review.

Banyameen Iqbal, Sushama Gurwale, Charusheela R Gore, Pragati Gupta

Abstract readCase Reports
In one paragraph

Article in Journal of mid-life health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Banyameen IqbalDepartment of Pathology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth, Pune, Maharashtra, India.
Sushama GurwaleDepartment of Pathology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth, Pune, Maharashtra, India.
Charusheela R GoreDepartment of Pathology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth, Pune, Maharashtra, India.
Pragati GuptaDepartment of Pathology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth, Pune, Maharashtra, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary squamous cell carcinoma (SCC) of the breast is classified by the World Health Organization as a metaplastic carcinoma, meaning that it is made up solely of squamous cells that have undergone metaplasia and frequently show variable degrees of keratinization. Less than 0.1% of all invasive breast carcinomas are primary SCCs, making them incredibly uncommon. The exact cause and development of SCC in the breast remain uncertain. Some suggest it could represent an extreme form of squamous cell metaplasia progressing into adenocarcinoma, potentially explaining its mixed forms. Existing literature reveals only a handful of documented cases to date. This malignancy is notably aggressive, typically lacking hormone receptor expression (triple negative), resistant to standard treatments, and associated with a bad prognosis.

Indexed as

Breastmetaplastic carcinomasquamous cell carcinomatriple negative

Identifiers

PMID40951857
PMCPMC12431709

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.