ArticleChemical science2025
Data-driven recommendation of agents, temperature, and equivalence ratios for organic synthesis.
Article in Chemical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Transforming Molecular Synthesis With Large Language Models.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026Review
- Organic Chemistry as a Catalyst for AI Innovation: Challenges, Methods, and Emerging Paradigms.Chemical reviews · 2026Review
- Flow Modeling, Reactor Engineering, and Process Intensification: From Insight to Performance.ACS engineering Au · 2026Review
- Looking back and to the future after four-plus years of language in chemistry.Digital discovery · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The identification of suitable reaction conditions is a crucial step in organic synthesis. Computer-aided synthesis planning promises to improve the efficiency of chemistry and enable robot-assisted workflows, but there remains a gap in bridging computational tools with experimental execution due to the challenge of reaction condition prediction. The conditions used to carry out a reaction consist of qualitative details, such as the discrete identities of "above-the-arrow" agents (catalysts, additives, solvents,
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.