ArticleJournal of Indian Society of Periodontology
Chairside clinicomicrobiological assessment of subgingival boric acid irrigation in periodontitis patients: A randomized controlled trial.
Article in Journal of Indian Society of Periodontology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Elemental boron has a positive role in many functions in the human body, such as immune regulation, wound healing, bone health maintenance, etc. A boron-containing molecule (AN0128) has shown additional antimicrobial properties against virulent red-complex bacteria. However, there is a dearth of human trials evaluating the effectiveness of readily available boronic compounds in periodontitis patients. Materials and Methods: Thirty-six patients with generalized periodontitis were included in this double-blind, placebo-controlled randomized clinical trial. Following scaling and root planing at baseline, each designated test site in the 18 treatment group subjects received subgingival 0.75% boric acid, whereas the remaining 18 subjects received placebo irrigation at the control site. At the 6 Results: Comparatively, the test group demonstrated significant improvements ( Conclusion: Outcomes of the present trial demonstrated boron's significant role in clinical improvements. Adjunctive subgingival boric acid irrigation can be effective in healing following phase-I therapy.
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