ArticleIBRO neuroscience reports2025
Diagnostic value of inflammatory indexes combined with myocardial enzymes for aneurysmal subarachnoid hemorrhage in patients with intracranial aneurysms.
Article in IBRO neuroscience reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Relationship Between Clinical Factors and the Risk of Cerebral Vasospasm Following Aneurysmal Subarachnoid Hemorrhage: An Exploratory Analysis.Life (Basel, Switzerland) · 2025Article
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4 authors.
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Abstract
Objective: The purpose of the study is to evaluate the diagnostic ability of inflammatory indexes alone and in combination with myocardial enzymes in the prediction of aneurysmal subarachnoid hemorrhage (aSAH). Materials and methods: This is a 1:1 age- and sex-matched case-control study in Tianjin, China. 226 patients aged > 18 years divided into aSAH group and unruptured intracranial aneurysm (UIA) group. Logistic regression models assessed associations between inflammatory indexes/myocardial enzymes and aSAH. Receiver operating characteristic (ROC) curves evaluated their sensitivity/specificity for aSAH. Results: Higher neutrophil-to-lymphocyte ratio (NLR) (OR: 1.130, 95 % CI: 1.074, 1.188), monocyte-to-lymphocyte ratio (MLR) (OR: 11.144, 95 % CI: 3.071, 40.437), platelet-to-lymphocyte ratio (PLR) (OR: 1.006, 95 % CI: 1.003, 1.008), systemic immune-inflammatory index (SII) (OR: 1.000, 95 % CI: 1.000, 1.001) and systemic inflammation response index (SIRI) (OR: 1.228, 95 % CI: 1.112, 1.357), myocardial enzymes lactate dehydrogenase (LDH) (OR: 1.008, 95 % CI: 1.003, 1.014), creatine kinase (CK) (OR: 1.002, 95 % CI: 1.000, 1.004), and α-hydroxybutyrate dehydrogenase (HBDH) (OR: 1.010, 95 % CI: 1.002, 1.018) were all significantly associated with the presence of aSAH. The diagnostic value of inflammatory indexes (NLR-PLR-MLR-SII-SIRI) and myocardial enzymes (LDH-HBDH-CK-CKMB) gave an AUC of 0.771 and 0.662 (all Conclusions: The results suggest that higher inflammatory indexes and myocardial enzymes were associated with the presence of aSAH. The combination of inflammatory indexes and myocardial enzymes may serve as a diagnostic complement for identifying aSAH in patients with IA.
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