Evidence map›Paper›PMID 40951619›Full record

ArticleJournal of the colleges of medicine of South Africa2025

The role of high-resolution manometry in a resource challenged service.

Mohammed A Parker, Mogamad S Gabriel, Muhammed S Moolla, Christoffel J van Rensburg, Desiree L Moodley, Wesley P du Plessis, Ahmad A Abdelsalem

Abstract read
In one paragraph

Article in Journal of the colleges of medicine of South Africa, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mohammed A ParkerDivision of Gastroenterology and Hepatology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg Hospital, Cape Town, South Africa.ORCID https://orcid.org/0000-0001-5742-8903
Mogamad S GabrielDivision of Gastroenterology and Hepatology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg Hospital, Cape Town, South Africa.ORCID https://orcid.org/0009-0008-1479-9948
Muhammed S MoollaDivision of Pulmonology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg Hospital, Cape Town, South Africa.ORCID https://orcid.org/0000-0003-0274-6909
Christoffel J van RensburgDivision of Gastroenterology and Hepatology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg Hospital, Cape Town, South Africa.ORCID https://orcid.org/0000-0002-3039-5918
Desiree L MoodleyDivision of Gastroenterology and Hepatology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg Hospital, Cape Town, South Africa.ORCID https://orcid.org/0009-0003-6703-5822
Wesley P du PlessisDivision of Gastroenterology and Hepatology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg Hospital, Cape Town, South Africa.ORCID https://orcid.org/0009-0007-2824-0646
Ahmad A AbdelsalemDivision of Gastroenterology and Hepatology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg Hospital, Cape Town, South Africa.ORCID https://orcid.org/0009-0009-5823-556X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Oesophageal high-resolution manometry (HRM) is commonly used in the evaluation of patients presenting with upper gastrointestinal tract symptoms where primary oesophageal motility disorders are suspected. At our hospital, one doctor can perform and interpret HRM, with the hospital serving a population of approximately 3 million people. There is a paucity of data on HRM findings in South Africa. Methods: This study included data from patients that underwent HRM between January 2018 and January 2023, using the hospitals electronic note-keeping system to access records. High-resolution manometry was performed for all patients using a water state catheter with 24 pressure channels. The Chicago classification version 3 was used for reporting. Results: A total of 210 patients were included in this study. The average age of patients included was 50 years (standard deviation [s.d.] ± 15.2) old with a female predominance ( Conclusion: This study, being the first of its kind in South Africa, highlights the role of HRM in the diagnosis of primary oesophageal motility disorders with ineffective oesophageal motility being the most common pathology and GORD being the most common indication for HRM. Achalasia type 1 was the common type diagnosed. Contribution: HRM, despite its scarce availability, remains an important diagnostic tool in evaluating gastrointestinal pathologies.

Indexed as

achalasiaChicago classificationhigh-resolution manometryineffective oesophageal motilityoesophageal motility disordersSouth Africa

Identifiers

PMID40951619
PMCPMC12424042

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.