Evidence map›Paper›PMID 40951604›Full record

ArticleJournal of the colleges of medicine of South Africa2025

Factors influencing delayed presentation of periorbital carcinoma requiring orbital exenteration.

Nadine van Wyk, Akiel Asvat, Mokokomadi A Makgotloe, Mantoa Mokhachane

Abstract read
In one paragraph

Article in Journal of the colleges of medicine of South Africa, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nadine van WykDivision of Ophthalmology, Department of Neurosciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID https://orcid.org/0009-0001-6656-6897
Akiel AsvatDivision of Ophthalmology, Department of Neurosciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID https://orcid.org/0000-0002-4622-120X
Mokokomadi A MakgotloeDivision of Ophthalmology, Department of Neurosciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID https://orcid.org/0000-0002-8193-3245
Mantoa MokhachaneUnit for Undergraduate Medical Education, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID https://orcid.org/0000-0001-5596-3654

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Ocular surface squamous neoplasia is the most widespread indication for orbital exenteration and the presenting feature of human immunodeficiency virus (HIV) in 50% to 86% of patients in endemic areas. Overall survival at 1 year post-exenteration ranged from 69.1% to 97.0%, according to a review article, with the lower rate attributed to delayed referral. Methods: A qualitative, descriptive phenomenological study was conducted to identify factors responsible for delayed presentation in advanced periorbital carcinoma requiring orbital exenteration. A total of 25 participants were enrolled using convenience sampling. Data were collected by means of a structured questionnaire and open-ended questions. The questionnaire was conducted as a semi-structured interview and recorded with a voice recorder, and the interviews were coded and themes were identified. Data were analysed using Colaizzi's seven steps for thematic analysis. Results: Six major themes were identified: a disregard for the seriousness of the condition; financial constraints; delays caused by the clinic; alternative treatment sought; stigma and fear; and relief and hope. Conclusion: Participants acknowledged that the mass was ignored. However, once healthcare was sought, many felt treatment was delayed as they had to wait for results or because of delayed appointment dates. A lack of financial freedom and a fear of loss of income further delayed participants. Traditional healers were sought as an adjunct to allopathic medicine to appease family. Stigma surrounding the loss of an eye burdened and alienated participants, but many were able to look to the future and forge a new hope and identity. Contribution: This study contributes to our understanding of the patient-related and systemic factors leading to delay. It highlights key barriers and and promotes earlier diagnosis and intervention.

Indexed as

delayed presentationexenterationophthalmologyperiorbital carcinomaqualitativetertiary hospital

Identifiers

PMID40951604
PMCPMC12424028

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.